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==Crystal structure of YPT32 in complex with GDP==
==Crystal structure of YPT32 in complex with GDP==
<StructureSection load='3rwo' size='340' side='right' caption='[[3rwo]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='3rwo' size='340' side='right'caption='[[3rwo]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3rwo]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RWO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RWO FirstGlance]. <br>
<table><tr><td colspan='2'>[[3rwo]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RWO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RWO FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3rwm|3rwm]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3rwm|3rwm]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">YGL210W, YPT11, YPT32 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">YGL210W, YPT11, YPT32 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rwo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rwo OCA], [http://pdbe.org/3rwo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3rwo RCSB], [http://www.ebi.ac.uk/pdbsum/3rwo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3rwo ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rwo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rwo OCA], [https://pdbe.org/3rwo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rwo RCSB], [https://www.ebi.ac.uk/pdbsum/3rwo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rwo ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/YPT32_YEAST YPT32_YEAST]] Required for protein transport through the secretory pathway. Probably involved in regulation of secretory vesicle formation at the trans-Golgi compartment. Mediates the proper polarized localization of SEC2, a GEF for SEC4, but does not alter the exchange activity of SEC2 on SEC4. Plays a role in autophagy.<ref>PMID:12045183</ref> <ref>PMID:12478387</ref> <ref>PMID:23078654</ref> <ref>PMID:8978673</ref> <ref>PMID:9151665</ref>   
[[https://www.uniprot.org/uniprot/YPT32_YEAST YPT32_YEAST]] Required for protein transport through the secretory pathway. Probably involved in regulation of secretory vesicle formation at the trans-Golgi compartment. Mediates the proper polarized localization of SEC2, a GEF for SEC4, but does not alter the exchange activity of SEC2 on SEC4. Plays a role in autophagy.<ref>PMID:12045183</ref> <ref>PMID:12478387</ref> <ref>PMID:23078654</ref> <ref>PMID:8978673</ref> <ref>PMID:9151665</ref>   
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[GTP-binding protein|GTP-binding protein]]
*[[GTP-binding protein 3D structures|GTP-binding protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Baker's yeast]]
[[Category: Baker's yeast]]
[[Category: Large Structures]]
[[Category: Dregger, C]]
[[Category: Dregger, C]]
[[Category: Franklin, E]]
[[Category: Franklin, E]]
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