5mle: Difference between revisions
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==Crystal Structure of Human Dihydropyrimidinease-like 2 (DPYSL2A)/Collapsin Response Mediator Protein (CRMP2 13-516) Mutant Y479E/Y499E== | |||
<StructureSection load='5mle' size='340' side='right' caption='[[5mle]], [[Resolution|resolution]] 2.48Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5mle]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MLE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5MLE FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5mle FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mle OCA], [http://pdbe.org/5mle PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mle RCSB], [http://www.ebi.ac.uk/pdbsum/5mle PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mle ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/DPYL2_HUMAN DPYL2_HUMAN]] Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton (By similarity). Plays a role in neuron projection morphogenesis.<ref>PMID:11477421</ref> <ref>PMID:15466863</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Ahmed, A A]] | |||
[[Category: Arrowsmith, C H]] | |||
[[Category: Bountra, C]] | |||
[[Category: Delft, F von]] | |||
[[Category: Edwards, A M]] | |||
[[Category: Sethi, R]] | |||
[[Category: Talon, R]] | |||
[[Category: Velupillai, S]] | |||
[[Category: Zheng, Y]] | |||
[[Category: Crmp2]] | |||
[[Category: Hydrolase]] | |||
[[Category: Microtubule associated protein]] | |||
[[Category: Ovarian cancer]] | |||
[[Category: Phospho-mutant]] | |||
Revision as of 01:39, 11 March 2017
Crystal Structure of Human Dihydropyrimidinease-like 2 (DPYSL2A)/Collapsin Response Mediator Protein (CRMP2 13-516) Mutant Y479E/Y499E
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