4h5p: Difference between revisions
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==Crystal Structure of Rift Valley Fever Virus Nucleocapsid Protein Tetramer Bound to Single-stranded RNA== | ==Crystal Structure of Rift Valley Fever Virus Nucleocapsid Protein Tetramer Bound to Single-stranded RNA== | ||
<StructureSection load='4h5p' size='340' side='right' caption='[[4h5p]], [[Resolution|resolution]] 2.15Å' scene=''> | <StructureSection load='4h5p' size='340' side='right'caption='[[4h5p]], [[Resolution|resolution]] 2.15Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4h5p]] is a 6 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4h5p]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Rift_Valley_fever_virus Rift Valley fever virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H5P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4H5P FirstGlance]. <br> | ||
</td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4h5p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h5p OCA], [https://pdbe.org/4h5p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4h5p RCSB], [https://www.ebi.ac.uk/pdbsum/4h5p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4h5p ProSAT]</span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/NCAP_RVFV NCAP_RVFV] Encapsidates the genomic RNA, protecting it from nucleases (Probable) (PubMed:20547879). Displays high affinity for single-stranded nucleic acid (PubMed:23129612). The encapsidated genomic RNA is termed the nucleocapsid (NC) or ribonucleoprotein (PubMed:20547879). The ribonucleoprotein has a non-helical structure (PubMed:20547879). Serves as template for viral transcription and replication (By similarity). After replication, the nucleocapsid is recruited to the host Golgi apparatus by glycoprotein Gn for packaging into virus particles (By similarity).[UniProtKB:P21700]<ref>PMID:20547879</ref> <ref>PMID:23129612</ref> <ref>PMID:34960686</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Rift Valley fever virus]] | ||
[[Category: | [[Category: Raymond DD]] | ||
[[Category: | [[Category: Smith JL]] | ||
