5m0j: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5m0j is ~~ON HOLD until Paper Publication~~

==Crystal structure of the cytoplasmic complex with She2p, She3p, and the ASH1 mRNA E3-localization element==

~~Authors~~: ~~Edelmann~~, F.T., ~~Janowski~~, R., ~~Niessing~~, D.

== Structural highlights ==

<table><tr><td colspan='2'>[[5m0j]] is a 10 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M0J OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5M0J FirstGlance].

~~Description~~: ~~Crystal structure~~ of the ~~cytoplasmic~~ complex ~~with She2p, She3p,~~ and ~~the~~ ASH1 mRNA ~~E3-localization element~~

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[5m0h|5m0h]], [[5m0i|5m0i]]</td></tr>

[[Category: ~~Edelmann~~, ~~F.T~~]]

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5m0j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m0j OCA], [http://pdbe.org/5m0j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5m0j RCSB], [http://www.ebi.ac.uk/pdbsum/5m0j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5m0j ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/SHE2_YEAS1 SHE2_YEAS1]] RNA-binding protein that binds specific mRNAs including the ASH1 mRNA, coding for a repressor of the HO endonuclease. Part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud and in the daughter cell. Recruits the MYO4-SHE3 complex to the ASH1 mRNA. Recruits also LOC1 and PUF6 to ASH1 mRNA, which are required for translational repression of this mRNA (By similarity).

__TOC__

</StructureSection>

[[Category: Edelmann, F T]]

[[Category: Janowski, R]]

[[Category: Niessing, D]]

[[Category: ~~Janowski, R~~]]

[[Category: Ash1-mrna]]

[[Category: Mrna transport]]

[[Category: Rna binding protein]]

[[Category: She2p]]

[[Category: She3p]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5m0j is ON HOLD  until Paper Publication
+==Crystal structure of the cytoplasmic complex with She2p, She3p, and the ASH1 mRNA E3-localization element==
+<StructureSection load='5m0j' size='340' side='right' caption='[[5m0j]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
-Authors: Edelmann, F.T., Janowski, R., Niessing, D.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5m0j]] is a 10 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M0J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5M0J FirstGlance]. <br>
-Description: Crystal structure of the cytoplasmic complex with She2p, She3p, and the ASH1 mRNA E3-localization element
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5m0h|5m0h]], [[5m0i|5m0i]]</td></tr>
-[[Category: Edelmann, F.T]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5m0j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m0j OCA], [http://pdbe.org/5m0j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5m0j RCSB], [http://www.ebi.ac.uk/pdbsum/5m0j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5m0j ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/SHE2_YEAS1 SHE2_YEAS1]] RNA-binding protein that binds specific mRNAs including the ASH1 mRNA, coding for a repressor of the HO endonuclease. Part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud and in the daughter cell. Recruits the MYO4-SHE3 complex to the ASH1 mRNA. Recruits also LOC1 and PUF6 to ASH1 mRNA, which are required for translational repression of this mRNA (By similarity).
+__TOC__
+</StructureSection>
+[[Category: Edelmann, F T]]
+[[Category: Janowski, R]]
 [[Category: Niessing, D]]
-[[Category: Janowski, R]]
+[[Category: Ash1-mrna]]
+[[Category: Mrna transport]]
+[[Category: Rna binding protein]]
+[[Category: She2p]]
+[[Category: She3p]]