5k89: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5k89 ~~is ON HOLD until Paper Publication~~

==Crystal Structure of Human Calcium-Bound S100A1==

~~Authors~~: ~~Melville, Z~~., ~~Aligholizadeh~~, E., ~~McKnight, L~~.E., ~~Weber~~, D., ~~Pozharski, E~~., ~~Weber, D~~.J.

== Structural highlights ==

<table><tr><td colspan='2'>[[5k89]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5K89 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5K89 FirstGlance]. <br>

~~Description~~: ~~Crystal Structure~~ of ~~Human Calcium~~-~~Bound S100A1~~

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5k89 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5k89 OCA], [http://pdbe.org/5k89 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5k89 RCSB], [http://www.ebi.ac.uk/pdbsum/5k89 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5k89 ProSAT]</span></td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/S10A1_HUMAN S10A1_HUMAN]] Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites.

__TOC__

</StructureSection>

[[Category: Aligholizadeh, E]]

[[Category: McKnight, L E]]

[[Category: Melville, Z]]

[[Category: Pozharski, E]]

~~[[Category: Mcknight, L.E]]~~

[[Category: Weber, D]]

[[Category: Weber, D.J]]

[[Category: Weber, D J]]

[[Category: ~~Aligholizadeh, E~~]]

[[Category: Calcium]]

[[Category: Metal binding protein]]

[[Category: S100]]

[[Category: S100a1]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5k89 is ON HOLD  until Paper Publication
+==Crystal Structure of Human Calcium-Bound S100A1==
+<StructureSection load='5k89' size='340' side='right' caption='[[5k89]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
-Authors: Melville, Z., Aligholizadeh, E., McKnight, L.E., Weber, D., Pozharski, E., Weber, D.J.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5k89]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5K89 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5K89 FirstGlance]. <br>
-Description: Crystal Structure of Human Calcium-Bound S100A1
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5k89 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5k89 OCA], [http://pdbe.org/5k89 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5k89 RCSB], [http://www.ebi.ac.uk/pdbsum/5k89 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5k89 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/S10A1_HUMAN S10A1_HUMAN]] Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites.
+__TOC__
+</StructureSection>
+[[Category: Aligholizadeh, E]]
+[[Category: McKnight, L E]]
 [[Category: Melville, Z]]
 [[Category: Pozharski, E]]
-[[Category: Mcknight, L.E]]
 [[Category: Weber, D]]
-[[Category: Weber, D.J]]
+[[Category: Weber, D J]]
-[[Category: Aligholizadeh, E]]
+[[Category: Calcium]]
+[[Category: Metal binding protein]]
+[[Category: S100]]
+[[Category: S100a1]]