5mr9: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5mr9 is ~~ON HOLD~~

==Ligand-receptor complex.==

~~Authors~~: ~~Sandmark~~, J., ~~Oster~~, L., ~~Aagaard, A~~.~~, Roth, R~~.G., ~~Dahl, G~~.

== Structural highlights ==

<table><tr><td colspan='2'>[[5mr9]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MR9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5MR9 FirstGlance]. <br>

~~Description~~: ~~Ligand-receptor complex~~.

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5mr9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mr9 OCA], [http://pdbe.org/5mr9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mr9 RCSB], [http://www.ebi.ac.uk/pdbsum/5mr9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mr9 ProSAT]</span></td></tr>

[[~~Category~~: ~~Unreleased Structures~~]]

</table>

== Disease ==

[[http://www.uniprot.org/uniprot/NRTN_HUMAN NRTN_HUMAN]] Hirschsprung disease. Genetic variations in NRTN may contribute to Hirschsprung disease, in association with mutations of RET gene, and possibly mutations in other loci. Hirschsprung disease is a disorder of neural crest development is characterized by the absence of intramural ganglion cells in the hindgut, often resulting in intestinal obstruction.<ref>PMID:9700200</ref>

== Function ==

[[http://www.uniprot.org/uniprot/NRTN_HUMAN NRTN_HUMAN]] Supports the survival of sympathetic neurons in culture. May regulate the development and maintenance of the CNS. Might control the size of non-neuronal cell population such as haemopoietic cells.

== References ==

__TOC__

</StructureSection>

[[Category: Aagaard, A]]

[[Category: Dahl, G]]

[[Category: Oster, L]]

~~[[Category: Dahl, G]]~~

[[Category: Roth, R G]]

[[Category: Roth, R.G]]

[[Category: Sandmark, J]]

[[Category: Complex]]

[[Category: Receptor]]

[[Category: Signaling protein]]

[[Category: Signalling]]

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5mr9 is ON HOLD
+==Ligand-receptor complex.==
+<StructureSection load='5mr9' size='340' side='right' caption='[[5mr9]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
-Authors: Sandmark, J., Oster, L., Aagaard, A., Roth, R.G., Dahl, G.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5mr9]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MR9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5MR9 FirstGlance]. <br>
-Description: Ligand-receptor complex.
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5mr9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mr9 OCA], [http://pdbe.org/5mr9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mr9 RCSB], [http://www.ebi.ac.uk/pdbsum/5mr9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mr9 ProSAT]</span></td></tr>
-[[Category: Unreleased Structures]]
+</table>
+== Disease ==
+[[http://www.uniprot.org/uniprot/NRTN_HUMAN NRTN_HUMAN]] Hirschsprung disease. Genetic variations in NRTN may contribute to Hirschsprung disease, in association with mutations of RET gene, and possibly mutations in other loci. Hirschsprung disease is a disorder of neural crest development is characterized by the absence of intramural ganglion cells in the hindgut, often resulting in intestinal obstruction.<ref>PMID:9700200</ref>
+== Function ==
+[[http://www.uniprot.org/uniprot/NRTN_HUMAN NRTN_HUMAN]] Supports the survival of sympathetic neurons in culture. May regulate the development and maintenance of the CNS. Might control the size of non-neuronal cell population such as haemopoietic cells.
+== References ==
+<references/>
+__TOC__
+</StructureSection>
 [[Category: Aagaard, A]]
+[[Category: Dahl, G]]
 [[Category: Oster, L]]
-[[Category: Dahl, G]]
+[[Category: Roth, R G]]
-[[Category: Roth, R.G]]
 [[Category: Sandmark, J]]
+[[Category: Complex]]
+[[Category: Receptor]]
+[[Category: Signaling protein]]
+[[Category: Signalling]]