5jdk: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5jdk is ~~ON HOLD~~ ~~until Paper Publication~~

==Crystal structure of the DNA binding domain of Sap1 in fission yeast S.pombe==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[5jdk]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JDK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JDK FirstGlance]. <br>

~~Description~~:

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5jdk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jdk OCA], [http://pdbe.org/5jdk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jdk RCSB], [http://www.ebi.ac.uk/pdbsum/5jdk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jdk ProSAT]</span></td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/SAP1_SCHPO SAP1_SCHPO]] Binds to sequences required for mating-type switching. Makes a simultaneous contact with both the alpha and beta domains of the switch-activating site SAS1. Also binds to replication fork barrier 1 (RFB1) located within a 78 base pair sequence near the 3' end of the rRNA coding region. This leads to replication fork blockage. It binds the consensus sequence 5'-TA[AG]GCAGNTN[CT]AACG[AC]G-3'. Has a role in chromosome organization and integrity where it is involved in chromosome segregation. Has a role in sister chromatid cohesion and condensation.

__TOC__

</StructureSection>

[[Category: He, P]]

[[Category: Wang, T]]

[[Category: Alpha-helix]]

[[Category: Dna binding protein]]

[[Category: Dna replication]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5jdk is ON HOLD  until Paper Publication
+==Crystal structure of the DNA binding domain of Sap1 in fission yeast S.pombe==
+<StructureSection load='5jdk' size='340' side='right' caption='[[5jdk]], [[Resolution|resolution]] 1.00&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5jdk]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JDK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JDK FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5jdk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jdk OCA], [http://pdbe.org/5jdk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jdk RCSB], [http://www.ebi.ac.uk/pdbsum/5jdk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jdk ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/SAP1_SCHPO SAP1_SCHPO]] Binds to sequences required for mating-type switching. Makes a simultaneous contact with both the alpha and beta domains of the switch-activating site SAS1. Also binds to replication fork barrier 1 (RFB1) located within a 78 base pair sequence near the 3' end of the rRNA coding region. This leads to replication fork blockage. It binds the consensus sequence 5'-TA[AG]GCAGNTN[CT]AACG[AC]G-3'.  Has a role in chromosome organization and integrity where it is involved in chromosome segregation. Has a role in sister chromatid cohesion and condensation.
+__TOC__
+</StructureSection>
+[[Category: He, P]]
+[[Category: Wang, T]]
+[[Category: Alpha-helix]]
+[[Category: Dna binding protein]]
+[[Category: Dna replication]]