OBrochtasSandbox: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
==O'Brochta's Sandbox == 0 | ==O'Brochta's Sandbox == 0 | ||
<StructureSection load='Model.itasser.relax.pdb' size='400' side='right' caption='Anopheles arabiensis InR kinase domain model' scene name=' | <StructureSection load='Model.itasser.relax.pdb' size='400' side='right' caption='Anopheles arabiensis InR kinase domain model' scene name='Insert optional scene name here' /> | ||
The Anopheles arabiensis Insulin Receptor's kinase domain was modeled by Brian Pierce for the 'An arab ts lethal project' | The Anopheles arabiensis Insulin Receptor's kinase domain was modeled by Brian Pierce for the 'An arab ts lethal project' | ||
Revision as of 21:19, 15 January 2017
==O'Brochta's Sandbox == 0
|
The Anopheles arabiensis Insulin Receptor's kinase domain was modeled by Brian Pierce for the 'An arab ts lethal project'
This shows the basic structure of the kinase domain with an N and C lobe. The ATP will sit between them just below Beta 1
This shows the ATP binding site (purple) and the catalytic loop (green). Here it is as a spacefilled model.
These are three ts mutations found in other RTKs.
G1000S (magenta), A1133G (orange), T1221I (teal)
And as a spacefilled model
