OBrochtasSandbox: Difference between revisions
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This <scene name='75/750300/T1221_spacefilled/1'>threonine</scene> when mutated to isoleucine resulted in ts lethal mutations in the sevenless and EGFR-like genes in D. melanogster | This <scene name='75/750300/T1221_spacefilled/1'>threonine</scene> when mutated to isoleucine resulted in ts lethal mutations in the sevenless and EGFR-like genes in D. melanogster | ||
Using the software TS_pred (a ts mutation prediction program): these are the <scene name='75/750300/Geneticmutations-tspred_rosett/ | Using the software TS_pred (a ts mutation prediction program): these are the <scene name='75/750300/Geneticmutations-tspred_rosett/2'>5 best sites</scene> to mutate based on sequence and structure - L1236, I1071, V1196, L1197,I1258 (red) | ||
Using Rosetta_ts_rbf (another ts mutation prediction program): these are the <scene name='75/750300/Geneticmutations-tspred_rosett/ | Using Rosetta_ts_rbf (another ts mutation prediction program): these are the <scene name='75/750300/Geneticmutations-tspred_rosett/2'>top 5</scene> sites -W1173P, M1075K, Y1208G, L1197P, Y1208Asn (yellow) | ||
Both TS_pred and Rosetta_ts_rbf had L1197 in their top 5 (black) | |||
