1rlr: Difference between revisions
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
[[Image:1rlr.jpg|left|200px]] | [[Image:1rlr.jpg|left|200px]] | ||
<!-- | |||
The line below this paragraph, containing "STRUCTURE_1rlr", creates the "Structure Box" on the page. | |||
You may change the PDB parameter (which sets the PDB file loaded into the applet) | |||
or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | |||
or leave the SCENE parameter empty for the default display. | |||
| | --> | ||
| | {{STRUCTURE_1rlr| PDB=1rlr | SCENE= }} | ||
}} | |||
'''STRUCTURE OF RIBONUCLEOTIDE REDUCTASE PROTEIN R1''' | '''STRUCTURE OF RIBONUCLEOTIDE REDUCTASE PROTEIN R1''' | ||
| Line 28: | Line 25: | ||
[[Category: Eklund, H.]] | [[Category: Eklund, H.]] | ||
[[Category: Uhlin, U.]] | [[Category: Uhlin, U.]] | ||
[[Category: | [[Category: Oxidoreductase]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 07:39:09 2008'' | |||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | |||
Revision as of 04:39, 3 May 2008
STRUCTURE OF RIBONUCLEOTIDE REDUCTASE PROTEIN R1
Overview
Ribonucleotide reductase is the only enzyme that catalyses de novo formation of deoxyribonucleotides and is thus a key enzyme in DNA synthesis. The radical-based reaction involves five cysteins. Two redox-active cysteines are located at adjacent antiparallel strands in a new type of ten-stranded alpha/beta-barrel, and two others at the carboxyl end in a flexible arm. The fifth cysteine, in a loop in the centre of the barrel, is positioned to initiate the radical reaction.
About this Structure
1RLR is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.
Reference
Structure of ribonucleotide reductase protein R1., Uhlin U, Eklund H, Nature. 1994 Aug 18;370(6490):533-9. PMID:8052308 Page seeded by OCA on Sat May 3 07:39:09 2008
