Genetics322 Sandbox DNA

3D DNA structure for class 1

B DNA

spinqualitylabelsall models B DNA Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Anything in this section will appear adjacent to the 3D structure and will be scrollable. This is the B form of DNA Here are the bases. Here are the nucleotides dA (blue), dG (red), dC (green), dT Here are the Major and Minor grooves. Here is the surface of the grooves Methyl groups of dT in the major grove. And here is the same view of the surface.

spinqualitylabelsall models Insert caption here Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D

This is a transcriptional repressor protein from E. coli. It binds specifically to particular sequences. You can see how the parts of the protein interact with the edges of the bases in both the major and minor grooves.

Here it is showing the surface of the protein. Look how it 'fits' into the major and minor grooves. This is a highly specific binding protein and only binds to this sequence. This is a chemical interaction.

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Proteopedia Page Contributors and Editors (what is this?)

David O'Brochta