5u8l: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
==Crystal structure of EGFR kinase domain in complex with a sulfonyl fluoride probe XO44== | ==Crystal structure of EGFR kinase domain in complex with a sulfonyl fluoride probe XO44== | ||
<StructureSection load='5u8l' size='340' side='right' caption='[[5u8l]], [[Resolution|resolution]] 1.60Å' scene=''> | <StructureSection load='5u8l' size='340' side='right'caption='[[5u8l]], [[Resolution|resolution]] 1.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5u8l]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5U8L OCA]. For a <b>guided tour on the structure components</b> use [http:// | <table><tr><td colspan='2'>[[5u8l]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5U8L OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5U8L FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=O44:4-[(4-{4-[(3-CYCLOPROPYL-1H-PYRAZOL-5-YL)AMINO]-6-[(PROP-2-YN-1-YL)CARBAMOYL]PYRIMIDIN-2-YL}PIPERAZIN-1-YL)METHYL]BENZENE-1-SULFONYL+FLUORIDE'>O44</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=O44:4-[(4-{4-[(3-CYCLOPROPYL-1H-PYRAZOL-5-YL)AMINO]-6-[(PROP-2-YN-1-YL)CARBAMOYL]PYRIMIDIN-2-YL}PIPERAZIN-1-YL)METHYL]BENZENE-1-SULFONYL+FLUORIDE'>O44</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">EGFR, ERBB, ERBB1, HER1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http:// | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5u8l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5u8l OCA], [http://pdbe.org/5u8l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5u8l RCSB], [http://www.ebi.ac.uk/pdbsum/5u8l PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5u8l ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Disease == | == Disease == | ||
| Line 21: | Line 22: | ||
</div> | </div> | ||
<div class="pdbe-citations 5u8l" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5u8l" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Epidermal growth factor receptor 3D structures|Epidermal growth factor receptor 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Human]] | |||
[[Category: Large Structures]] | |||
[[Category: Receptor protein-tyrosine kinase]] | [[Category: Receptor protein-tyrosine kinase]] | ||
[[Category: Ferre, R]] | [[Category: Ferre, R]] | ||
