1s1w: Difference between revisions

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[[Image:1s1w.gif|left|200px]]
[[Image:1s1w.gif|left|200px]]


{{Structure
<!--
|PDB= 1s1w |SIZE=350|CAPTION= <scene name='initialview01'>1s1w</scene>, resolution 2.70&Aring;
The line below this paragraph, containing "STRUCTURE_1s1w", creates the "Structure Box" on the page.
|SITE=
You may change the PDB parameter (which sets the PDB file loaded into the applet)
|LIGAND= <scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene>, <scene name='pdbligand=UC1:2-METHYL-FURAN-3-CARBOTHIOIC+ACID+[4-CHLORO-3-(3-METHYL-BUT-2-ENYLOXY)-PHENYL]-AMIDE'>UC1</scene>
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/RNA-directed_DNA_polymerase RNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.49 2.7.7.49] </span>
or leave the SCENE parameter empty for the default display.
|GENE= POL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id= Human immunodeficiency virus type 1 (isolate HXB2)])
-->
|DOMAIN=
{{STRUCTURE_1s1w|  PDB=1s1w |  SCENE= }}  
|RELATEDENTRY=[[1vrt|1VRT]], [[1rth|1RTH]], [[1vru|1VRU]], [[1rti|1RTI]], [[1rtj|1RTJ]], [[1rev|1REV]], [[1rt1|1RT1]], [[1rt2|1RT2]], [[1klm|1KLM]], [[1rt3|1RT3]], [[1rt4|1RT4]], [[1rt5|1RT5]], [[1rt6|1RT6]], [[1rt7|1RT7]], [[1c0t|1C0T]], [[1c0u|1C0U]], [[1c1b|1C1B]], [[1c1c|1C1C]], [[1dtq|1DTQ]], [[1dtt|1DTT]], [[1ep4|1EP4]], [[1fk9|1FK9]], [[1fko|1FKO]], [[1fkp|1FKP]], [[1jla|1JLA]], [[1jlb|1JLB]], [[1jlc|1JLC]], [[1jle|1JLE]], [[1jlf|1JLF]], [[1jlg|1JLG]], [[1jkh|1JKH]], [[1jlq|1JLQ]], [[1lw0|1LW0]], [[1lw2|1LW2]], [[1lwc|1LWC]], [[1lwe|1LWE]], [[1lwf|1LWF]], [[1s1t|1S1T]], [[1s1u|1S1U]], [[1s1v|1S1V]], [[1s1x|1S1X]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1s1w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s1w OCA], [http://www.ebi.ac.uk/pdbsum/1s1w PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1s1w RCSB]</span>
}}


'''Crystal structure of V106A mutant HIV-1 reverse transcriptase in complex with UC-781'''
'''Crystal structure of V106A mutant HIV-1 reverse transcriptase in complex with UC-781'''
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==Reference==
==Reference==
Crystal structures of HIV-1 reverse transcriptases mutated at codons 100, 106 and 108 and mechanisms of resistance to non-nucleoside inhibitors., Ren J, Nichols CE, Chamberlain PP, Weaver KL, Short SA, Stammers DK, J Mol Biol. 2004 Feb 20;336(3):569-78. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15095972 15095972]
Crystal structures of HIV-1 reverse transcriptases mutated at codons 100, 106 and 108 and mechanisms of resistance to non-nucleoside inhibitors., Ren J, Nichols CE, Chamberlain PP, Weaver KL, Short SA, Stammers DK, J Mol Biol. 2004 Feb 20;336(3):569-78. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15095972 15095972]
[[Category: Human immunodeficiency virus type 1 (isolate hxb2)]]
[[Category: Protein complex]]
[[Category: Protein complex]]
[[Category: RNA-directed DNA polymerase]]
[[Category: RNA-directed DNA polymerase]]
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[[Category: Ren, J.]]
[[Category: Ren, J.]]
[[Category: Stammers, D K.]]
[[Category: Stammers, D K.]]
[[Category: aid]]
[[Category: Aid]]
[[Category: drug resistance mutation]]
[[Category: Drug resistance mutation]]
[[Category: hiv-1 reverse transcriptase]]
[[Category: Hiv-1 reverse transcriptase]]
[[Category: nnrti]]
[[Category: Nnrti]]
[[Category: uc-781]]
[[Category: Uc-781]]
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:36:10 2008''
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