IGF1: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 16: | Line 16: | ||
== Biological structures and interactions == | == Biological structures and interactions == | ||
In the pituitary gland inside the brain, Growth Hormone (GH) is secreted and its release enable transcription of IGF-1 in liver and depending on the nutritional state a paracrine or autocrine activation IGF-1 occurs. Once in the cell, IGF-1 acts as a ligand and can interact with Insulin Receptor protein and Insulin-like Growth Factor Binding Protein. | |||
=== Structures === | === Structures === | ||
IGF-1 is a 8.28 kDa protein consisting of 69 amino acids. | IGF-1 is a 8.28 kDa protein consisting of 69 amino acids. | ||