5lmf: Difference between revisions

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'''Unreleased structure'''


The entry 5lmf is ON HOLD  until Paper Publication
==Yeast protein peptide complex==
 
<StructureSection load='5lmf' size='340' side='right' caption='[[5lmf]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
Authors: Charenton, C., Gaudon-Plesse, C., Fourati, Z., Taverniti, V., Back, R., Kolesnikova, O., Seraphin, B., Graille, M.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[5lmf]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LMF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LMF FirstGlance]. <br>
Description: Yeast protein peptide complex
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5lmf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lmf OCA], [http://pdbe.org/5lmf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5lmf RCSB], [http://www.ebi.ac.uk/pdbsum/5lmf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5lmf ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/PAT1_YEAST PAT1_YEAST]] Activator of decapping that functions as a general and active mechanism of translational repression and required for P-body formation. First decay factor recruited to mRNA, at a time when the mRNA is still associated with translation factors. Subsequently, PAT1 recruits the hepta-heterodimer LSM1-LSM7 complex to P-bodies. In association with the LSM1-LSM7 complex, stabilizes the 3' terminus of mRNAs. This association is also required for mosaic virus genomic RNA translation. Modulates the rates of mRNA-decapping that occur following deadenylation. Might be required for promoting the formation or the stabilization of the preinitiation translation complexes. Required for 40S ribosomal subunit joining to capped and/or polyadenylated mRNA. With other P-body components, enhances the formation of retrotransposition-competent Ty1 virus-like particles. Necessary for accurate chromosome transmission during cell division.<ref>PMID:8816497</ref> <ref>PMID:8972867</ref> <ref>PMID:10523645</ref> <ref>PMID:10394921</ref> <ref>PMID:10747033</ref> <ref>PMID:10779343</ref> <ref>PMID:10913177</ref> <ref>PMID:11027264</ref> <ref>PMID:10761922</ref> <ref>PMID:11514438</ref> <ref>PMID:12773554</ref> <ref>PMID:16179257</ref> <ref>PMID:17875743</ref> <ref>PMID:17429074</ref> <ref>PMID:17513695</ref> <ref>PMID:18086885</ref> <ref>PMID:19901074</ref> <ref>PMID:20832728</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Back, R]]
[[Category: Back, R]]
[[Category: Charenton, C]]
[[Category: Fourati, Z]]
[[Category: Gaudon-Plesse, C]]
[[Category: Graille, M]]
[[Category: Graille, M]]
[[Category: Kolesnikova, O]]
[[Category: Seraphin, B]]
[[Category: Seraphin, B]]
[[Category: Charenton, C]]
[[Category: Gaudon-Plesse, C]]
[[Category: Fourati, Z]]
[[Category: Taverniti, V]]
[[Category: Taverniti, V]]
[[Category: Kolesnikova, O]]
[[Category: Isomerase]]
[[Category: Protein peptide complex]]
[[Category: Rna binding protein]]