5m4z: Difference between revisions
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==Crystal structure of the complex of T.spiralis thymidylate synthase with N(4)-hydroxy-2'-deoxycytidine-5'-monophosphate, crystallized in the presence of N(5,10)-methylenetetrahydrofolate== | |||
<StructureSection load='5m4z' size='340' side='right' caption='[[5m4z]], [[Resolution|resolution]] 1.18Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5m4z]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M4Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5M4Z FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7K8:[(2~{R},3~{S},5~{R})-5-[(4~{E})-4-hydroxyimino-2-oxidanylidene-1,3-diazinan-1-yl]-3-oxidanyl-oxolan-2-yl]methyl+dihydrogen+phosphate'>7K8</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | |||
[[ | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thymidylate_synthase Thymidylate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.45 2.1.1.45] </span></td></tr> | ||
[[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5m4z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m4z OCA], [http://pdbe.org/5m4z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5m4z RCSB], [http://www.ebi.ac.uk/pdbsum/5m4z PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5m4z ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Thymidylate synthase]] | |||
[[Category: Dowiercial, A]] | [[Category: Dowiercial, A]] | ||
[[Category: Jarmula, A]] | [[Category: Jarmula, A]] | ||
[[Category: Maj, P]] | [[Category: Maj, P]] | ||
[[Category: Rode, W]] | |||
[[Category: Wilk, P]] | |||
[[Category: Anticancer target]] | |||
[[Category: Enzyme-inhibitor complex]] | |||
[[Category: High-resolution structure]] | |||
[[Category: Transferase]] | |||
Revision as of 06:04, 20 December 2017
Crystal structure of the complex of T.spiralis thymidylate synthase with N(4)-hydroxy-2'-deoxycytidine-5'-monophosphate, crystallized in the presence of N(5,10)-methylenetetrahydrofolate
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