5m7a: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5m7a is ~~ON HOLD until Paper Publication~~

==Blood group synthase AAGlyB in complex with UMP and cryoprotected with PEG 3350==

~~Authors~~: ~~Rocha~~, J., ~~Royant~~, A.

== Structural highlights ==

<table><tr><td colspan='2'>[[5m7a]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M7A OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5M7A FirstGlance].

~~Description~~: ~~Blood~~ group ~~synthase AAGlyB in complex with UMP~~ and ~~cryoprotected with PEG 3350~~

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=U5P:URIDINE-5-MONOPHOSPHATE'>U5P</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[3zgf|3zgf]], [[3zgg|3zgg]], [[5m79|5m79]]</td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5m7a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m7a OCA], [http://pdbe.org/5m7a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5m7a RCSB], [http://www.ebi.ac.uk/pdbsum/5m7a PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5m7a ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/BGAT_HUMAN BGAT_HUMAN]] This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity.

__TOC__

</StructureSection>

[[Category: Rocha, J]]

[[Category: Royant, A]]

[[Category: ~~Rocha, J~~]]

[[Category: Blood group synthase]]

[[Category: Cis-ab mutant]]

[[Category: Dual-specificity]]

[[Category: Glycosyltransferase]]

[[Category: Transferase]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5m7a is ON HOLD  until Paper Publication
+==Blood group synthase AAGlyB in complex with UMP and cryoprotected with PEG 3350==
+<StructureSection load='5m7a' size='340' side='right' caption='[[5m7a]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
-Authors: Rocha, J., Royant, A.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5m7a]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M7A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5M7A FirstGlance]. <br>
-Description: Blood group synthase AAGlyB in complex with UMP and cryoprotected with PEG 3350
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=U5P:URIDINE-5-MONOPHOSPHATE'>U5P</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3zgf|3zgf]], [[3zgg|3zgg]], [[5m79|5m79]]</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5m7a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m7a OCA], [http://pdbe.org/5m7a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5m7a RCSB], [http://www.ebi.ac.uk/pdbsum/5m7a PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5m7a ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/BGAT_HUMAN BGAT_HUMAN]] This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity.
+__TOC__
+</StructureSection>
+[[Category: Rocha, J]]
 [[Category: Royant, A]]
-[[Category: Rocha, J]]
+[[Category: Blood group synthase]]
+[[Category: Cis-ab mutant]]
+[[Category: Dual-specificity]]
+[[Category: Glycosyltransferase]]
+[[Category: Transferase]]