5n7y: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5n7y is ~~ON HOLD~~

==Solution structure of B. subtilis Sigma G inhibitor CsfB==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[5n7y]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5N7Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5N7Y FirstGlance]. <br>

~~Description~~:

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5n7y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5n7y OCA], [http://pdbe.org/5n7y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5n7y RCSB], [http://www.ebi.ac.uk/pdbsum/5n7y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5n7y ProSAT]</span></td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/GIN_BACSU GIN_BACSU]] An anti-sigma-G factor, prevents premature activation of sigma-G factor in the forespore; overexpression leads to 1000-fold reduction in spore formation, spore formation stops after engulfment (PubMed:17921305, PubMed:19497328). Overexpression also inhibits sigma-G transcription activation activity (PubMed:18208527). When both Gin and sigma-G are expressed in E.coli Gin inhibits sigma-G, strongly suggesting Gin inhibits by direct physical interaction (PubMed:19497328).<ref>PMID:17921305</ref> <ref>PMID:18208527</ref> <ref>PMID:19497328</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Alfano, C]]

[[Category: Atkinson, A]]

[[Category: Isaacson, R L]]

[[Category: Martinez-Lumbreras, S]]

[[Category: Csfb]]

[[Category: Dimer]]

[[Category: Sigma g inhibitor]]

[[Category: Transcription]]

[[Category: Zinc-finger]]

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5n7y is ON HOLD
+==Solution structure of B. subtilis Sigma G inhibitor CsfB==
+<StructureSection load='5n7y' size='340' side='right' caption='[[5n7y]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5n7y]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5N7Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5N7Y FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5n7y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5n7y OCA], [http://pdbe.org/5n7y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5n7y RCSB], [http://www.ebi.ac.uk/pdbsum/5n7y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5n7y ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/GIN_BACSU GIN_BACSU]] An anti-sigma-G factor, prevents premature activation of sigma-G factor in the forespore; overexpression leads to 1000-fold reduction in spore formation, spore formation stops after engulfment (PubMed:17921305, PubMed:19497328). Overexpression also inhibits sigma-G transcription activation activity (PubMed:18208527). When both Gin and sigma-G are expressed in E.coli Gin inhibits sigma-G, strongly suggesting Gin inhibits by direct physical interaction (PubMed:19497328).<ref>PMID:17921305</ref> <ref>PMID:18208527</ref> <ref>PMID:19497328</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Alfano, C]]
+[[Category: Atkinson, A]]
+[[Category: Isaacson, R L]]
+[[Category: Martinez-Lumbreras, S]]
+[[Category: Csfb]]
+[[Category: Dimer]]
+[[Category: Sigma g inhibitor]]
+[[Category: Transcription]]
+[[Category: Zinc-finger]]