5n8v: Difference between revisions
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==Targeting the PEX14-PEX5 interaction by small molecules provides novel therapeutic routes to treat trypanosomiases.== | |||
<StructureSection load='5n8v' size='340' side='right' caption='[[5n8v]], [[Resolution|resolution]] 1.55Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5n8v]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5N8V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5N8V FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=KZZ:1-(2-AZANYLETHYL)-5-[(4-METHOXYNAPHTHALEN-1-YL)METHYL]-~{N}-(NAPHTHALEN-1-YLMETHYL)-6,7-DIHYDRO-4~{H}-PYRAZOLO[4,3-C]PYRIDINE-3-CARBOXAMIDE'>KZZ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
[[ | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5l8a|5l8a]], [[5l87|5l87]]</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5n8v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5n8v OCA], [http://pdbe.org/5n8v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5n8v RCSB], [http://www.ebi.ac.uk/pdbsum/5n8v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5n8v ProSAT]</span></td></tr> | |||
</table> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Dawidowski, M]] | [[Category: Dawidowski, M]] | ||
[[Category: Emmanouilidis, L]] | [[Category: Emmanouilidis, L]] | ||
[[Category: Popowicz, G M]] | |||
[[Category: Sattler, M]] | [[Category: Sattler, M]] | ||
[[Category: Glycosome]] | |||
[[Category: Inhibitor]] | |||
[[Category: Protein-protein interaction inhibitor]] | |||
[[Category: Signaling protein]] | |||
[[Category: Structure-based drug discovery]] | |||
[[Category: Trypanosomiasis]] | |||
