5u0k: Difference between revisions
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==C-terminal ankyrin repeats from human liver-type glutaminase (GAB/LGA)== | |||
<StructureSection load='5u0k' size='340' side='right' caption='[[5u0k]], [[Resolution|resolution]] 2.55Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5u0k]] is a 10 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5U0K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5U0K FirstGlance]. <br> | |||
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5u0i|5u0i]], [[5u0j|5u0j]]</td></tr> | |||
[[Category: | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutaminase Glutaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.2 3.5.1.2] </span></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5u0k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5u0k OCA], [http://pdbe.org/5u0k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5u0k RCSB], [http://www.ebi.ac.uk/pdbsum/5u0k PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5u0k ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/GLSL_HUMAN GLSL_HUMAN]] Plays an important role in the regulation of glutamine catabolism. Promotes mitochondrial respiration and increases ATP generation in cells by catalyzing the synthesis of glutamate and alpha-ketoglutarate. Increases cellular anti-oxidant function via NADH and glutathione production. May play a role in preventing tumor proliferation.<ref>PMID:20378837</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Glutaminase]] | |||
[[Category: Ambrosio, A L.B]] | |||
[[Category: Dias, S M.G]] | |||
[[Category: Ferreira, I M]] | |||
[[Category: Gonzalez, A]] | [[Category: Gonzalez, A]] | ||
[[Category: | [[Category: Pascoal, C C]] | ||
[[Category: | [[Category: Ankyrin]] | ||
[[Category: | [[Category: Gls2]] | ||
[[Category: Human]] | |||
[[Category: Hydrolase]] | |||
Revision as of 13:49, 24 May 2017
C-terminal ankyrin repeats from human liver-type glutaminase (GAB/LGA)
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