1t7i: Difference between revisions

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[[Image:1t7i.gif|left|200px]]
[[Image:1t7i.gif|left|200px]]


{{Structure
<!--
|PDB= 1t7i |SIZE=350|CAPTION= <scene name='initialview01'>1t7i</scene>, resolution 1.35&Aring;
The line below this paragraph, containing "STRUCTURE_1t7i", creates the "Structure Box" on the page.
|SITE=
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
|LIGAND= <scene name='pdbligand=017:(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE'>017</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] </span>
or leave the SCENE parameter empty for the default display.
|GENE= POL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 Human immunodeficiency virus 1])
-->
|DOMAIN=
{{STRUCTURE_1t7i| PDB=1t7i  | SCENE= }}  
|RELATEDENTRY=[[1f7a|1F7A]], [[1t3r|1T3R]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1t7i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t7i OCA], [http://www.ebi.ac.uk/pdbsum/1t7i PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1t7i RCSB]</span>
}}


'''The structural and thermodynamic basis for the binding of TMC114, a next-generation HIV-1 protease inhibitor.'''
'''The structural and thermodynamic basis for the binding of TMC114, a next-generation HIV-1 protease inhibitor.'''
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[[Category: Schiffer, C A.]]
[[Category: Schiffer, C A.]]
[[Category: Wigerinck, P B.T P.]]
[[Category: Wigerinck, P B.T P.]]
[[Category: drug resitance]]
[[Category: Drug resitance]]
[[Category: hiv-1 protease]]
[[Category: Hiv-1 protease]]
[[Category: substrate envelope]]
[[Category: Substrate envelope]]
[[Category: thermodynamic]]
[[Category: Thermodynamic]]
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:52:21 2008''
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