5ncm: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5ncm is ~~ON HOLD until Paper Publication~~

==Crystal structure Cbk1(NTR)-Mob2 complex==

~~Authors~~: ~~Gogl~~, G., ~~Remenyi~~, A., ~~Parker~~, B., ~~Weiss, E~~.

== Structural highlights ==

<table><tr><td colspan='2'>[[5ncm]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NCM OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NCM FirstGlance].

~~Description~~: ~~Crystal structure Cbk1~~(~~NTR~~)-~~Mob2 complex~~

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>

[[~~Category~~: ~~Unreleased Structures~~]]

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </td></tr>

[[Category: ~~Weiss, E~~]]

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ncm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ncm OCA], [http://pdbe.org/5ncm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ncm RCSB], [http://www.ebi.ac.uk/pdbsum/5ncm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ncm ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/MOB2_YEAST MOB2_YEAST]] Functions as an activator subunit for the CBK1 protein kinase. Part of the regulation of ACE2 activity and cellular morphogenesis (RAM) signaling network. Required for coordinating polarized cell growth during interphase with the onset of mitosis. Required for mother/daughter cell separation after cytokinesis. Also has a role in the prevention of nuclear export of ACE2 from the daughter cell nucleus after mitotic exit. It coordinates ACE2-dependent transcription with mitotic exit network activation.<ref>PMID:11747810</ref> <ref>PMID:12196508</ref> [[http://www.uniprot.org/uniprot/CBK1_YEAST CBK1_YEAST]] Protein kinase that seems to play a role in the regulation of cell morphogenesis and proliferation.

== References ==

__TOC__

</StructureSection>

[[Category: Non-specific serine/threonine protein kinase]]

[[Category: Gogl, G]]

[[Category: Parker, B]]

[[Category: Remenyi, A]]

[[Category: ~~Parker~~, B]]

[[Category: Weiss, E]]

[[Category: Kinase]]

[[Category: Signaling protein]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5ncm is ON HOLD  until Paper Publication
+==Crystal structure Cbk1(NTR)-Mob2 complex==
+<StructureSection load='5ncm' size='340' side='right' caption='[[5ncm]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
-Authors: Gogl, G., Remenyi, A., Parker, B., Weiss, E.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5ncm]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NCM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NCM FirstGlance]. <br>
-Description: Crystal structure Cbk1(NTR)-Mob2 complex
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
-[[Category: Weiss, E]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ncm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ncm OCA], [http://pdbe.org/5ncm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ncm RCSB], [http://www.ebi.ac.uk/pdbsum/5ncm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ncm ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/MOB2_YEAST MOB2_YEAST]] Functions as an activator subunit for the CBK1 protein kinase. Part of the regulation of ACE2 activity and cellular morphogenesis (RAM) signaling network. Required for coordinating polarized cell growth during interphase with the onset of mitosis. Required for mother/daughter cell separation after cytokinesis. Also has a role in the prevention of nuclear export of ACE2 from the daughter cell nucleus after mitotic exit. It coordinates ACE2-dependent transcription with mitotic exit network activation.<ref>PMID:11747810</ref> <ref>PMID:12196508</ref>  [[http://www.uniprot.org/uniprot/CBK1_YEAST CBK1_YEAST]] Protein kinase that seems to play a role in the regulation of cell morphogenesis and proliferation.
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Non-specific serine/threonine protein kinase]]
 [[Category: Gogl, G]]
+[[Category: Parker, B]]
 [[Category: Remenyi, A]]
-[[Category: Parker, B]]
+[[Category: Weiss, E]]
+[[Category: Kinase]]
+[[Category: Signaling protein]]