User:Madelyn Smith/Sandbox 1: Difference between revisions

From Proteopedia
Jump to navigationJump to search
No edit summary
No edit summary
Line 8: Line 8:
*Molecular Weight: 700.792 g/mol  
*Molecular Weight: 700.792 g/mol  
*IUPAC name: 4-[4-[4-[4-[[(3R,5R)-5-(2,4-difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-[(2S,3S)-2-hydroxypentan-3-yl]-1,2,4-triazol-3-one
*IUPAC name: 4-[4-[4-[4-[[(3R,5R)-5-(2,4-difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-[(2S,3S)-2-hydroxypentan-3-yl]-1,2,4-triazol-3-one
The structure of Posaconazole allows it to potently act as a triazole broad-spectrum antifungal drug that was derived from the antifungal agent, Itraconazole. The differences in structure are that the Chlorine substituents in the aromatic ring on the left-hand side of the images are replaces with Fluorines and that the triazolone sidechain is hydroxylated in the Posaconazole structure<ref>PMID: 21059682 <ref/>.
The structure of Posaconazole allows it to potently act as a triazole broad-spectrum antifungal drug that was derived from the antifungal agent, Itraconazole. The differences in structure are that the Chlorine substituents in the aromatic ring on the left-hand side of the images are replaces with Fluorines and that the triazolone sidechain is hydroxylated in the Posaconazole structure<ref>PMID: 21059682 </ref>.


== Function ==
== Function ==