Transaldolase

spinqualitylabelsall models Transaldolase dimer complex with sedoheptulose 7-phosphate and Cl- (green) ion, 3tno Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function Transaldolase (TAL) is part of the pentose phosphate pathway. It catalyzes the transformation of sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate to erythrose 4-phosphate and fructose 6-phosphate. Disease TAL deficiency influences mitochondrial homeostasis, Ca+2 fluxing and apoptosis. Structural highlights TAL overall structure is of a TIM barrel. Alpha Helices,  Beta Strands ,  Loops , Turns. The active site contains a Schiff-base-bound phosphosugar at Lys135. 3D Structures of transaldolase Updated on 02-April-2017 {"openlevels":0} Transaldolase 3clm – TAL – Neisseria gonorrhoeae 3cwn, 1onr, 1ucw - EcTAL B – Escherichia coli 3kof, 1i2n, 1i2o, 1i2p, 1i2q, 1i2r, 4rz5, 4rz6 - EcTAL B (mutant) 3hjz – TAL B – Prochlorococcus marinus 3igx, 4e0c – FtTAL B – Francisella tularensis 3m16 – TAL – Oleispira Antarctica 3r8r – TAL – Bacillus subtilis 3r5e – TAL – Corynebacterium glutamicum 1f05 – TAL – human 1vpx – TAL – Thermotoga maritima 1wx0 – TAL – Thermus thermophilus 2cwn, 2e1d – TAL (mutant) – mouse Transaldolase binary complexes 3tk7 - FtTAL B + fructose 6-phosphate 3te9 - FtTAL B (mutant) + fructose 6-phosphate 3tkf - FtTAL B (mutant) + seduheptulose 7-phosphate 3tno - FtTAL B + seduheptulose 7-phosphate 3upb - FtTAL B + arabinose 5-phosphate 4s2b - EcTAL B + tagatose 6-phosphate 4s2c, 4s1f - EcTAL B + fructose 6-phosphate 4rxf, 4rxg, 4rz4 - EcTAL B (mutant) + fructose 6-phosphate 4xz9 - TAL + glycerol 3-phosphate – Thermoplasma acidophilum

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