5v8w: Difference between revisions
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The | ==Crystal structure of human Integrator IntS9-IntS11 CTD complex== | ||
<StructureSection load='5v8w' size='340' side='right' caption='[[5v8w]], [[Resolution|resolution]] 2.10Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5v8w]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V8W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5V8W FirstGlance]. <br> | |||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5v8w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5v8w OCA], [http://pdbe.org/5v8w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5v8w RCSB], [http://www.ebi.ac.uk/pdbsum/5v8w PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5v8w ProSAT]</span></td></tr> | |||
[[Category: | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/INT9_HUMAN INT9_HUMAN]] Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. [[http://www.uniprot.org/uniprot/INT11_HUMAN INT11_HUMAN]] Catalytic component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Mediates the snRNAs 3' cleavage.<ref>PMID:16239144</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Tong, L]] | |||
[[Category: Wu, Y]] | |||
[[Category: Hydrolase]] | |||
[[Category: Integrator complex]] | |||
[[Category: Snrna processing]] | |||
Revision as of 11:49, 12 April 2017
Crystal structure of human Integrator IntS9-IntS11 CTD complex
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