Sandbox GGC1: Difference between revisions

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== Function ==
== Function ==
The active site is referred to as the P1 position. The S1 binding pocket is responsible for stabilization of the P1 substrate prior to cleavage. The S1 pocket is mainly hydrophobic and preferentially binds to large, nonpolar amino acids, which includes P1 tyrosine, tryptophan, and phenylalanine. The <scene name='75/752263/Active_site/2'>S1 pocket</scene> of the bovine alpha-chymotrypsin is highlighted in yellow.
The S1 binding pocket is responsible for stabilization of the substrate prior to cleavage. The S1 pocket is mainly hydrophobic and preferentially binds to large, nonpolar amino acids, which includes tyrosine, tryptophan, and phenylalanine. The <scene name='75/752263/Active_site/2'>S1 pocket</scene> of the bovine alpha-chymotrypsin is highlighted in yellow.
== Disease ==
== Disease ==


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