5jkk: Difference between revisions

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'''Unreleased structure'''


The entry 5jkk is ON HOLD  until Paper Publication
==Crystal structure of the negatively supercharged variant Ftn(neg) of human heavy chain ferritin==
 
<StructureSection load='5jkk' size='340' side='right' caption='[[5jkk]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[5jkk]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JKK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JKK FirstGlance]. <br>
Description:  
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ferroxidase Ferroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.16.3.1 1.16.3.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5jkk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jkk OCA], [http://pdbe.org/5jkk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jkk RCSB], [http://www.ebi.ac.uk/pdbsum/5jkk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jkk ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/FRIH_HUMAN FRIH_HUMAN]] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity).
__TOC__
</StructureSection>
[[Category: Ferroxidase]]
[[Category: Beck, T]]
[[Category: Kuenzle, M]]
[[Category: Binary nanoparticle superlattice]]
[[Category: Binary protein structure]]
[[Category: Charged protein container]]
[[Category: Oxidoreductase]]
[[Category: Protein design]]
[[Category: Protein engineering]]
[[Category: Self-assembly]]