1ugl: Difference between revisions
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'''Solution structure of S8-SP11''' | '''Solution structure of S8-SP11''' | ||
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==About this Structure== | ==About this Structure== | ||
1UGL is a [[Single protein]] structure | 1UGL is a [[Single protein]] structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UGL OCA]. | ||
==Reference== | ==Reference== | ||
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[[Category: Shirakawa, M.]] | [[Category: Shirakawa, M.]] | ||
[[Category: Takayama, S.]] | [[Category: Takayama, S.]] | ||
[[Category: | [[Category: Cysteine-rich]] | ||
[[Category: | [[Category: Defensin-like]] | ||
[[Category: | [[Category: Male determinant of self-incompatibility]] | ||
[[Category: | [[Category: Nmr]] | ||
[[Category: | [[Category: Riken structural genomics/proteomics initiative]] | ||
[[Category: | [[Category: Rsgi]] | ||
[[Category: | [[Category: Scr]] | ||
[[Category: | [[Category: Sp11]] | ||
[[Category: | [[Category: Structural genomic]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 11:12:00 2008'' | |||
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Revision as of 08:12, 3 May 2008
Solution structure of S8-SP11
Overview
Many flowering plants possess a self-incompatibility system to prevent inbreeding. In Brassica rapa, self/non-self recognition in mating is established through S-haplotype-specific interactions between stigma receptors and S-locus protein 11 (SP11, also called S-locus cysteine-rich protein) that is encoded at the highly polymorphic S-locus. Here we describe the solution structure of the SP11 protein of the S8-haplotype (S8-SP11), which specifically binds to the stigma factor of the same haplotype. It folds into an alpha/beta sandwich structure that resembles those of plant defensins. Residues important for structural integrity are highly conserved among the allelic SP11s, suggesting the existence of a common folding pattern. Structure-based sequence alignment and homology modeling of allelic SP11 identified a hyper-variable (HV) region, which is thought to form a loop that bulges out from the body of the protein that is amenable to solvent exposure. We suggest that the HV region could serve as a specific binding site for the stigma receptor.
About this Structure
1UGL is a Single protein structure. Full crystallographic information is available from OCA.
Reference
Structure of the male determinant factor for Brassica self-incompatibility., Mishima M, Takayama S, Sasaki K, Jee JG, Kojima C, Isogai A, Shirakawa M, J Biol Chem. 2003 Sep 19;278(38):36389-95. Epub 2003 Jun 30. PMID:12835321 Page seeded by OCA on Sat May 3 11:12:00 2008
Proteopedia Page Contributors and Editors (what is this?)
- Pages with broken file links
- Single protein
- Isogai, A.
- Jee, J G.
- Kojima, C.
- Mishima, M.
- RSGI, RIKEN Structural Genomics/Proteomics Initiative.
- Sasaki, K.
- Shirakawa, M.
- Takayama, S.
- Cysteine-rich
- Defensin-like
- Male determinant of self-incompatibility
- Nmr
- Riken structural genomics/proteomics initiative
- Rsgi
- Scr
- Sp11
- Structural genomic
