5hbt: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5hbt ~~is ON HOLD until Jun 28 2018~~

==Complex structure of Fab35 and human nAChR alpha1==

~~Authors~~: ~~Noridomi~~, K., ~~Watanabe~~, G., ~~Hansen, M~~.N., ~~Han~~, G.W., ~~Chen~~, L.

== Structural highlights ==

<table><tr><td colspan='2'>[[5hbt]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/ ], [http://en.wikipedia.org/wiki/Bungarus_multicinctus Bungarus multicinctus] and [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HBT OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HBT FirstGlance].

~~Description~~: ~~Complex structure of Fab35~~ and ~~human~~ nAChR ~~alpha1~~

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[5hbv|5hbv]]</td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hbt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hbt OCA], [http://pdbe.org/5hbt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hbt RCSB], [http://www.ebi.ac.uk/pdbsum/5hbt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hbt ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/3L21V_BUNMU 3L21V_BUNMU]] Binds with high affinity to muscular (alpha-1/CHRNA1) and neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission.[UniProtKB:P60615]<ref>PMID:10497260</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Bungarus multicinctus]]

[[Category: Rattus norvegicus]]

[[Category: Chen, L]]

[[Category: Han, G W]]

[[Category: Hansen, M N]]

[[Category: Noridomi, K]]

~~[[Category: Hansen, M.N]]~~

[[Category: Watanabe, G]]

[[Category: ~~Han, G.W~~]]

[[Category: Complex]]

[[Category: ~~Chen, L~~]]

[[Category: Fab35]]

[[Category: Myasthenia gravi]]

[[Category: Nicotinic acetylcholine receptor alpha1]]

[[Category: Transport protein-toxin complex]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5hbt is ON HOLD  until Jun 28 2018
+==Complex structure of Fab35 and human nAChR alpha1==
+<StructureSection load='5hbt' size='340' side='right' caption='[[5hbt]], [[Resolution|resolution]] 2.61&Aring;' scene=''>
-Authors: Noridomi, K., Watanabe, G., Hansen, M.N., Han, G.W., Chen, L.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5hbt]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/ ], [http://en.wikipedia.org/wiki/Bungarus_multicinctus Bungarus multicinctus] and [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HBT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HBT FirstGlance]. <br>
-Description: Complex structure of Fab35 and human nAChR alpha1
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5hbv|5hbv]]</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hbt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hbt OCA], [http://pdbe.org/5hbt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hbt RCSB], [http://www.ebi.ac.uk/pdbsum/5hbt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hbt ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/3L21V_BUNMU 3L21V_BUNMU]] Binds with high affinity to muscular (alpha-1/CHRNA1) and neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission.[UniProtKB:P60615]<ref>PMID:10497260</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Bungarus multicinctus]]
+[[Category: Rattus norvegicus]]
+[[Category: Chen, L]]
+[[Category: Han, G W]]
+[[Category: Hansen, M N]]
 [[Category: Noridomi, K]]
-[[Category: Hansen, M.N]]
 [[Category: Watanabe, G]]
-[[Category: Han, G.W]]
+[[Category: Complex]]
-[[Category: Chen, L]]
+[[Category: Fab35]]
+[[Category: Myasthenia gravi]]
+[[Category: Nicotinic acetylcholine receptor alpha1]]
+[[Category: Transport protein-toxin complex]]