5vck: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry 5vck is ON HOLD until Paper Publication~~

==HIV Protease (PR) with TL-3 in the active site and (Z)-N-(thiazol-2-yl)-N'-tosylcarbamimidate in the exosite==

~~Authors: Tiefenbrunn, T., Stout, C.D.~~

== Structural highlights ==

<table><tr><td colspan='2'>[[5vck]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VCK OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5VCK FirstGlance].

~~Description:~~ HIV Protease (PR) with TL-3 in the active site and (Z)-N-(thiazol-2-yl)-N'-tosylcarbamimidate in the exosite

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=3TL:BENZYL+[(1S,4S,7S,8R,9R,10S,13S,16S)-7,10-DIBENZYL-8,9-DIHYDROXY-1,16-DIMETHYL-4,13-BIS(1-METHYLETHYL)-2,5,12,15,18-PENTAOXO-20-PHENYL-19-OXA-3,6,11,14,17-PENTAAZAICOS-1-YL]CARBAMATE'>3TL</scene>, <scene name='pdbligand=7GC:4-methyl-N-(thiazol-2-ylcarbamoyl)benzenesulfonamide'>7GC</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[5to9|5to9]]</td></tr>

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] </td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5vck FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vck OCA], [http://pdbe.org/5vck PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5vck RCSB], [http://www.ebi.ac.uk/pdbsum/5vck PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5vck ProSAT]</td></tr>

</table>

__TOC__

</StructureSection>

[[Category: HIV-1 retropepsin]]

[[Category: Stout, C D]]

[[Category: Tiefenbrunn, T]]

[[Category: ~~Stout, C.D~~]]

[[Category: Allostery]]

[[Category: Exosite]]

[[Category: Fragment binding]]

[[Category: Hydrolase]]

[[Category: Protease]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5vck is ON HOLD  until Paper Publication
+==HIV Protease (PR) with TL-3 in the active site and (Z)-N-(thiazol-2-yl)-N'-tosylcarbamimidate in the exosite==
+<StructureSection load='5vck' size='340' side='right' caption='[[5vck]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
-Authors: Tiefenbrunn, T., Stout, C.D.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5vck]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VCK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5VCK FirstGlance]. <br>
-Description: HIV Protease (PR) with TL-3 in the active site and (Z)-N-(thiazol-2-yl)-N'-tosylcarbamimidate in the exosite
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3TL:BENZYL+[(1S,4S,7S,8R,9R,10S,13S,16S)-7,10-DIBENZYL-8,9-DIHYDROXY-1,16-DIMETHYL-4,13-BIS(1-METHYLETHYL)-2,5,12,15,18-PENTAOXO-20-PHENYL-19-OXA-3,6,11,14,17-PENTAAZAICOS-1-YL]CARBAMATE'>3TL</scene>, <scene name='pdbligand=7GC:4-methyl-N-(thiazol-2-ylcarbamoyl)benzenesulfonamide'>7GC</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5to9|5to9]]</td></tr>
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5vck FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vck OCA], [http://pdbe.org/5vck PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5vck RCSB], [http://www.ebi.ac.uk/pdbsum/5vck PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5vck ProSAT]</span></td></tr>
+</table>
+__TOC__
+</StructureSection>
+[[Category: HIV-1 retropepsin]]
+[[Category: Stout, C D]]
 [[Category: Tiefenbrunn, T]]
-[[Category: Stout, C.D]]
+[[Category: Allostery]]
+[[Category: Exosite]]
+[[Category: Fragment binding]]
+[[Category: Hydrolase]]
+[[Category: Protease]]