5nzy: Difference between revisions
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==Crystal structure of DNA cross-link repair protein 1A in complex with Cefotaxime== | |||
<StructureSection load='5nzy' size='340' side='right' caption='[[5nzy]], [[Resolution|resolution]] 1.55Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5nzy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NZY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NZY FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CE3:(6R,7R)-3-(ACETYLOXYMETHYL)-7-[[(2Z)-2-(2-AMINO-1,3-THIAZOL-4-YL)-2-METHOXYIMINO-ETHANOYL]AMINO]-8-OXO-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLIC+ACID'>CE3</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr> | |||
[[ | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DCLRE1A, KIAA0086, SNM1, SNM1A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
[[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5nzy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nzy OCA], [http://pdbe.org/5nzy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5nzy RCSB], [http://www.ebi.ac.uk/pdbsum/5nzy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5nzy ProSAT]</span></td></tr> | ||
[[ | </table> | ||
[[Category: | == Function == | ||
[[http://www.uniprot.org/uniprot/DCR1A_HUMAN DCR1A_HUMAN]] May be required for DNA interstrand cross-link repair. Also required for checkpoint mediated cell cycle arrest in early prophase in response to mitotic spindle poisons.<ref>PMID:15542852</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Human]] | |||
[[Category: Aitkenhead, H]] | [[Category: Aitkenhead, H]] | ||
[[Category: | [[Category: Arrowsmith, C H]] | ||
[[Category: Bountra, C]] | |||
[[Category: Burgess-Brown, N A]] | |||
[[Category: Delft, F von]] | |||
[[Category: Edwards, A]] | |||
[[Category: Gileadi, O]] | [[Category: Gileadi, O]] | ||
[[Category: Krojer, T]] | [[Category: Krojer, T]] | ||
[[Category: Kupinska, K]] | [[Category: Kupinska, K]] | ||
[[Category: Newman, J A]] | |||
[[Category: Talon, R]] | |||
[[Category: Cephalosporin]] | |||
[[Category: Cross-link repair]] | |||
[[Category: Dclre1a]] | |||
[[Category: Dna binding protein]] | |||
[[Category: Exonulcease]] | |||
Revision as of 09:57, 16 November 2017
Crystal structure of DNA cross-link repair protein 1A in complex with Cefotaxime
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