4crc: Difference between revisions
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==Creating novel F1 inhibitors through fragment based lead generation and structure aided drug design== | ==Creating novel F1 inhibitors through fragment based lead generation and structure aided drug design== | ||
<StructureSection load='4crc' size='340' side='right' caption='[[4crc]], [[Resolution|resolution]] 1.60Å' scene=''> | <StructureSection load='4crc' size='340' side='right'caption='[[4crc]], [[Resolution|resolution]] 1.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4crc]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CRC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CRC FirstGlance]. <br> | <table><tr><td colspan='2'>[[4crc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CRC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CRC FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=OTM:(2S)-2-[[(E)-3-[5-CHLORANYL-2-(1,2,3,4-TETRAZOL-1-YL)PHENYL]PROP-2-ENOYL]AMINO]-3-PHENYL-N-[4-(1H-1,2,3,4-TETRAZOL-5-YL)PHENYL]PROPANAMIDE'>OTM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=OTM:(2S)-2-[[(E)-3-[5-CHLORANYL-2-(1,2,3,4-TETRAZOL-1-YL)PHENYL]PROP-2-ENOYL]AMINO]-3-PHENYL-N-[4-(1H-1,2,3,4-TETRAZOL-5-YL)PHENYL]PROPANAMIDE'>OTM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4cr5|4cr5]], [[4cr9|4cr9]], [[4cra|4cra]], [[4crb|4crb]], [[4crd|4crd]], [[4cre|4cre]], [[4crf|4crf]], [[4crg|4crg]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4cr5|4cr5]], [[4cr9|4cr9]], [[4cra|4cra]], [[4crb|4crb]], [[4crd|4crd]], [[4cre|4cre]], [[4crf|4crf]], [[4crg|4crg]]</td></tr> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Coagulation factor XIa]] | [[Category: Coagulation factor XIa]] | ||
[[Category: Human]] | |||
[[Category: Large Structures]] | |||
[[Category: Akkaya, S]] | [[Category: Akkaya, S]] | ||
[[Category: Beisel, H G]] | [[Category: Beisel, H G]] | ||
