Virus protease: Difference between revisions
From Proteopedia
Jump to navigationJump to search
Michal Harel (talk | contribs) No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
<StructureSection load='1odw' size='350' side='right' caption='HIV-1 protease dimer complex with tert-butylcarbonate [[1odw]]' scene=' /'> | |||
'''Virus proteases''' include HIV protease, XMRV protease, retropepsin. | '''Virus proteases''' include HIV protease, XMRV protease, retropepsin. | ||
HIV Protease (HIV-PR) and xenotropic murine leukemia virus protease (XMRV-PR) cleave polyproteins to produce the mature proteins of the virus. Both are aspartyl proteases. The inhibition of HIV-PR results in an uninfectious HIV virion. HIV-1 is found globally while HIV-2, which has lower virulence, is found in West Africa. | HIV Protease (HIV-PR) and xenotropic murine leukemia virus protease (XMRV-PR) cleave polyproteins to produce the mature proteins of the virus. Both are aspartyl proteases. The inhibition of HIV-PR results in an uninfectious HIV virion. HIV-1 is found globally while HIV-2, which has lower virulence, is found in West Africa. | ||
| Line 15: | Line 14: | ||
*[[Molecular Playground/Dengue Virus Protease]] | *[[Molecular Playground/Dengue Virus Protease]] | ||
</StructureSection> | |||
== 3D Structures of Virus proteases == | == 3D Structures of Virus proteases == | ||
