5ob5: Difference between revisions
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==fAb complex with GroBeta. AbVance: increasing our knowledge of antibody structural space to enable faster and better decision-making in antibody drug discovery.== | |||
<StructureSection load='5ob5' size='340' side='right' caption='[[5ob5]], [[Resolution|resolution]] 1.65Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5ob5]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OB5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5OB5 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ob5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ob5 OCA], [http://pdbe.org/5ob5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ob5 RCSB], [http://www.ebi.ac.uk/pdbsum/5ob5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ob5 ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/CXCL2_HUMAN CXCL2_HUMAN]] Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity.<ref>PMID:10725737</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Convery, M A]] | |||
[[Category: Ward, P]] | |||
[[Category: Zhao, B]] | [[Category: Zhao, B]] | ||
[[Category: | [[Category: Abvance project]] | ||
[[Category: | [[Category: Fab complex]] | ||
[[Category: Immune system]] | |||
[[Category: Pistoia alliance]] | |||
Revision as of 07:48, 8 November 2017
fAb complex with GroBeta. AbVance: increasing our knowledge of antibody structural space to enable faster and better decision-making in antibody drug discovery.
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