5oc9: Difference between revisions
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The entry | ==Crystal Structure of human TMEM16K / Anoctamin 10== | ||
<StructureSection load='5oc9' size='340' side='right' caption='[[5oc9]], [[Resolution|resolution]] 3.20Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5oc9]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OC9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5OC9 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=79M:(2R)-2,3-DIHYDROXYPROPYL+(7Z)-HEXADEC-7-ENOATE'>79M</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5oc9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5oc9 OCA], [http://pdbe.org/5oc9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5oc9 RCSB], [http://www.ebi.ac.uk/pdbsum/5oc9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5oc9 ProSAT]</span></td></tr> | ||
</table> | |||
== Disease == | |||
[[http://www.uniprot.org/uniprot/ANO10_HUMAN ANO10_HUMAN]] Adult-onset autosomal recessive cerebellar ataxia. The disease is caused by mutations affecting the gene represented in this entry. | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/ANO10_HUMAN ANO10_HUMAN]] Does not exhibit calcium-activated chloride channel (CaCC) activity. Can inhibit the activity of ANO1.<ref>PMID:20056604</ref> <ref>PMID:22946059</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Arrowsmith, C H]] | |||
[[Category: BORKOWSKA, O]] | |||
[[Category: Bountra, C]] | |||
[[Category: Burgess-Brown, N A]] | |||
[[Category: Bushell, S R]] | |||
[[Category: CHALK, R]] | |||
[[Category: Carpenter, E P]] | |||
[[Category: Chu, A]] | |||
[[Category: Edwards, A M]] | |||
[[Category: Kupinska, K]] | |||
[[Category: Love, J]] | |||
[[Category: Mukhopadhyay, S]] | |||
[[Category: Pike, A C.W]] | |||
[[Category: Rotty, B]] | |||
[[Category: Structural genomic]] | |||
[[Category: Shrestha, L]] | |||
[[Category: Tessitore, A]] | |||
[[Category: Calcium activation]] | |||
[[Category: Lipid transport]] | |||
[[Category: Membrane protein]] | |||
[[Category: Sgc]] | |||
[[Category: Transport protein]] | |||
