5vx1: Difference between revisions
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==Bak L100A== | |||
<StructureSection load='5vx1' size='340' side='right' caption='[[5vx1]], [[Resolution|resolution]] 1.22Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5vx1]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VX1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5VX1 FirstGlance]. <br> | |||
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5vwv|5vwv]], [[5vww|5vww]], [[5vwx|5vwx]], [[5vwy|5vwy]], [[5vwz|5vwz]], [[5vx0|5vx0]], [[5vx2|5vx2]], [[5vx3|5vx3]]</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5vx1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vx1 OCA], [http://pdbe.org/5vx1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5vx1 RCSB], [http://www.ebi.ac.uk/pdbsum/5vx1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5vx1 ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/BAK_HUMAN BAK_HUMAN]] In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti-apoptotic action of BCL2 or its adenovirus homolog E1B 19k protein. Low micromolar levels of zinc ions inhibit the promotion of apoptosis.<ref>PMID:8521816</ref> <ref>PMID:17157251</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Brouwer, J M]] | |||
[[Category: Colman, P M]] | |||
[[Category: Czabotar, P E]] | |||
[[Category: Apoptosis]] | |||
[[Category: Bcl-2 family]] | |||
[[Category: Mutant]] | |||
