5vxc: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5vxc is ~~ON HOLD~~ ~~until Paper Publication~~

==Crystal Structure Analysis of human CLYBL in complex with free CoASH==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[5vxc]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VXC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5VXC FirstGlance]. <br>

~~Description~~:

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5vxc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vxc OCA], [http://pdbe.org/5vxc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5vxc RCSB], [http://www.ebi.ac.uk/pdbsum/5vxc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5vxc ProSAT]</span></td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/CLYBL_HUMAN CLYBL_HUMAN]] Mitochondrial malate and beta-methylmalate synthase, which may be involved in vitamin B12 metabolism (Probable). Acts both as a malate synthase, converting glyoxylate and acetyl-CoA to malate. Also acts as a beta-methylmalate synthase by mediating conversion of glyoxylate and propionyl-CoA to beta-methylmalate (PubMed:24334609).<ref>PMID:24334609</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Shen, H]]

[[Category: Coash]]

[[Category: Formate form]]

[[Category: Lyase]]

[[Category: Trimer]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5vxc is ON HOLD  until Paper Publication
+==Crystal Structure Analysis of human CLYBL in complex with free CoASH==
+<StructureSection load='5vxc' size='340' side='right' caption='[[5vxc]], [[Resolution|resolution]] 1.87&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5vxc]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VXC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5VXC FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5vxc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vxc OCA], [http://pdbe.org/5vxc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5vxc RCSB], [http://www.ebi.ac.uk/pdbsum/5vxc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5vxc ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/CLYBL_HUMAN CLYBL_HUMAN]] Mitochondrial malate and beta-methylmalate synthase, which may be involved in vitamin B12 metabolism (Probable). Acts both as a malate synthase, converting glyoxylate and acetyl-CoA to malate. Also acts as a beta-methylmalate synthase by mediating conversion of glyoxylate and propionyl-CoA to beta-methylmalate (PubMed:24334609).<ref>PMID:24334609</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Shen, H]]
+[[Category: Coash]]
+[[Category: Formate form]]
+[[Category: Lyase]]
+[[Category: Trimer]]