5vxo: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5vxo is ~~ON HOLD~~ ~~until Paper Publication~~

==Crystal Structure Analysis of human CLYBL in complex with propionyl-CoA==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[5vxo]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VXO OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5VXO FirstGlance].

~~Description~~:

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=1VU:PROPIONYL+COENZYME+A'>1VU</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[5vxc|5vxc]]</td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5vxo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vxo OCA], [http://pdbe.org/5vxo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5vxo RCSB], [http://www.ebi.ac.uk/pdbsum/5vxo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5vxo ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/CLYBL_HUMAN CLYBL_HUMAN]] Mitochondrial malate and beta-methylmalate synthase, which may be involved in vitamin B12 metabolism (Probable). Acts both as a malate synthase, converting glyoxylate and acetyl-CoA to malate. Also acts as a beta-methylmalate synthase by mediating conversion of glyoxylate and propionyl-CoA to beta-methylmalate (PubMed:24334609).<ref>PMID:24334609</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Shen, H]]

[[Category: Citrate form]]

[[Category: Clybl]]

[[Category: Lyase]]

[[Category: Peg form]]

[[Category: Propionyl-coa]]

[[Category: Trimer]]

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5vxo is ON HOLD  until Paper Publication
+==Crystal Structure Analysis of human CLYBL in complex with propionyl-CoA==
+<StructureSection load='5vxo' size='340' side='right' caption='[[5vxo]], [[Resolution|resolution]] 2.27&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5vxo]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VXO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5VXO FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1VU:PROPIONYL+COENZYME+A'>1VU</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5vxc|5vxc]]</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5vxo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vxo OCA], [http://pdbe.org/5vxo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5vxo RCSB], [http://www.ebi.ac.uk/pdbsum/5vxo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5vxo ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/CLYBL_HUMAN CLYBL_HUMAN]] Mitochondrial malate and beta-methylmalate synthase, which may be involved in vitamin B12 metabolism (Probable). Acts both as a malate synthase, converting glyoxylate and acetyl-CoA to malate. Also acts as a beta-methylmalate synthase by mediating conversion of glyoxylate and propionyl-CoA to beta-methylmalate (PubMed:24334609).<ref>PMID:24334609</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Shen, H]]
+[[Category: Citrate form]]
+[[Category: Clybl]]
+[[Category: Lyase]]
+[[Category: Peg form]]
+[[Category: Propionyl-coa]]
+[[Category: Trimer]]