5w3g: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5w3g is ~~ON HOLD until Paper Publication~~

==Solution Structure of ETS Transcription Factor PU.1==

~~Authors~~: ~~Lau~~, D.K.W., ~~Okon~~, M., ~~McIntosh~~, L.P.

== Structural highlights ==

<table><tr><td colspan='2'>[[5w3g]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5W3G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5W3G FirstGlance]. <br>

~~Description~~: ~~Solution Structure of ETS Transcription Factor PU~~.1

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5w3g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5w3g OCA], [http://pdbe.org/5w3g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5w3g RCSB], [http://www.ebi.ac.uk/pdbsum/5w3g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5w3g ProSAT]</span></td></tr>

[[~~Category~~: ~~Unreleased Structures~~]]

</table>

[[Category: Lau, D.K.W]]

== Disease ==

[[http://www.uniprot.org/uniprot/SPI1_MOUSE SPI1_MOUSE]] Note=Involved in murine acute Friend erythroleukemia. It is a target region for SFFV proviral insertion.

== Function ==

[[http://www.uniprot.org/uniprot/SPI1_MOUSE SPI1_MOUSE]] Binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B-cells. Also binds RNA and may modulate pre-mRNA splicing.<ref>PMID:8626664</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Lau, D K.W]]

[[Category: McIntosh, L P]]

[[Category: Okon, M]]

[[Category: ~~Mcintosh, L.P~~]]

[[Category: Dna binding protein]]

[[Category: Winged helix-turn-helix]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5w3g is ON HOLD  until Paper Publication
+==Solution Structure of ETS Transcription Factor PU.1==
+<StructureSection load='5w3g' size='340' side='right' caption='[[5w3g]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
-Authors: Lau, D.K.W., Okon, M., McIntosh, L.P.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5w3g]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5W3G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5W3G FirstGlance]. <br>
-Description: Solution Structure of ETS Transcription Factor PU.1
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5w3g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5w3g OCA], [http://pdbe.org/5w3g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5w3g RCSB], [http://www.ebi.ac.uk/pdbsum/5w3g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5w3g ProSAT]</span></td></tr>
-[[Category: Unreleased Structures]]
+</table>
-[[Category: Lau, D.K.W]]
+== Disease ==
+[[http://www.uniprot.org/uniprot/SPI1_MOUSE SPI1_MOUSE]] Note=Involved in murine acute Friend erythroleukemia. It is a target region for SFFV proviral insertion.
+== Function ==
+[[http://www.uniprot.org/uniprot/SPI1_MOUSE SPI1_MOUSE]] Binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B-cells. Also binds RNA and may modulate pre-mRNA splicing.<ref>PMID:8626664</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Lau, D K.W]]
+[[Category: McIntosh, L P]]
 [[Category: Okon, M]]
-[[Category: Mcintosh, L.P]]
+[[Category: Dna binding protein]]
+[[Category: Winged helix-turn-helix]]