5w5w: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry 5w5w is ON HOLD until Paper Publication~~

==HIV Protease (PR) in open form with Mg2+ in active site and HIVE-9 in eye site==

~~Authors: Tiefenbrunn, T., Stout, C.D.~~

== Structural highlights ==

<table><tr><td colspan='2'>[[5w5w]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5W5W OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5W5W FirstGlance].

~~Description:~~ HIV Protease (PR) in open form with Mg2+ in active site and HIVE-9 in eye site

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=3TL:BENZYL+[(1S,4S,7S,8R,9R,10S,13S,16S)-7,10-DIBENZYL-8,9-DIHYDROXY-1,16-DIMETHYL-4,13-BIS(1-METHYLETHYL)-2,5,12,15,18-PENTAOXO-20-PHENYL-19-OXA-3,6,11,14,17-PENTAAZAICOS-1-YL]CARBAMATE'>3TL</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=HV9:4-methyl-N-({1-[4-(trifluoromethyl)pyrimidin-2-yl]piperidin-4-yl}carbamoyl)benzene-1-sulfonamide'>HV9</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[5vea|5vea]], [[5vck|5vck]], [[5vj3|5vj3]]</td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5w5w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5w5w OCA], [http://pdbe.org/5w5w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5w5w RCSB], [http://www.ebi.ac.uk/pdbsum/5w5w PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5w5w ProSAT]</td></tr>

</table>

__TOC__

</StructureSection>

[[Category: Stout, C D]]

[[Category: Tiefenbrunn, T]]

[[Category: ~~Stout, C.D~~]]

[[Category: Allostery]]

[[Category: Exosite]]

[[Category: Fragment binding]]

[[Category: Hydrolase]]

[[Category: Protease]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5w5w is ON HOLD  until Paper Publication
+==HIV Protease (PR) in open form with Mg2+ in active site and HIVE-9 in eye site==
+<StructureSection load='5w5w' size='340' side='right' caption='[[5w5w]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
-Authors: Tiefenbrunn, T., Stout, C.D.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5w5w]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5W5W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5W5W FirstGlance]. <br>
-Description: HIV Protease (PR) in open form with Mg2+ in active site and HIVE-9 in eye site
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3TL:BENZYL+[(1S,4S,7S,8R,9R,10S,13S,16S)-7,10-DIBENZYL-8,9-DIHYDROXY-1,16-DIMETHYL-4,13-BIS(1-METHYLETHYL)-2,5,12,15,18-PENTAOXO-20-PHENYL-19-OXA-3,6,11,14,17-PENTAAZAICOS-1-YL]CARBAMATE'>3TL</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=HV9:4-methyl-N-({1-[4-(trifluoromethyl)pyrimidin-2-yl]piperidin-4-yl}carbamoyl)benzene-1-sulfonamide'>HV9</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5vea|5vea]], [[5vck|5vck]], [[5vj3|5vj3]]</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5w5w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5w5w OCA], [http://pdbe.org/5w5w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5w5w RCSB], [http://www.ebi.ac.uk/pdbsum/5w5w PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5w5w ProSAT]</span></td></tr>
+</table>
+__TOC__
+</StructureSection>
+[[Category: Stout, C D]]
 [[Category: Tiefenbrunn, T]]
-[[Category: Stout, C.D]]
+[[Category: Allostery]]
+[[Category: Exosite]]
+[[Category: Fragment binding]]
+[[Category: Hydrolase]]
+[[Category: Protease]]