5w61: Difference between revisions
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==Crystal structure of BAXP168G monomer co-crystallized with glycerol== | |||
<StructureSection load='5w61' size='340' side='right' caption='[[5w61]], [[Resolution|resolution]] 2.30Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5w61]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5W61 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5W61 FirstGlance]. <br> | |||
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5w5x|5w5x]], [[5w5z|5w5z]], [[5w60|5w60]], [[5w62|5w62]], [[5w63|5w63]]</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5w61 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5w61 OCA], [http://pdbe.org/5w61 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5w61 RCSB], [http://www.ebi.ac.uk/pdbsum/5w61 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5w61 ProSAT]</span></td></tr> | ||
[[Category: Robin, A | </table> | ||
[[Category: | == Function == | ||
[[Category: | [[http://www.uniprot.org/uniprot/BAX_HUMAN BAX_HUMAN]] Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.<ref>PMID:8358790</ref> <ref>PMID:10772918</ref> <ref>PMID:8521816</ref> <ref>PMID:16113678</ref> <ref>PMID:18948948</ref> <ref>PMID:21199865</ref> | ||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Colman, P M]] | |||
[[Category: Czabotar, P E]] | |||
[[Category: Robin, A Y]] | |||
[[Category: Apoptosis]] | |||
[[Category: Bax]] | |||
[[Category: Inactive monomer]] | |||
Revision as of 05:27, 27 June 2018
Crystal structure of BAXP168G monomer co-crystallized with glycerol
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