5wdm: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5wdm is ~~ON HOLD until Paper Publication~~

==An ultra-stable single-chain insulin analog resists thermal inactivation and exhibits biological signaling duration equivalent to the native protein==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[5wdm]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WDM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WDM FirstGlance]. <br>

~~Description~~:

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wdm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wdm OCA], [http://pdbe.org/5wdm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wdm RCSB], [http://www.ebi.ac.uk/pdbsum/5wdm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wdm ProSAT]</span></td></tr>

[[Category: ~~Unreleased Structures~~]]

</table>

== Function ==

[[http://www.uniprot.org/uniprot/A6XGL2_HUMAN A6XGL2_HUMAN]] Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver (By similarity).[SAAS:SAAS022353_004_028339]

__TOC__

</StructureSection>

[[Category: Aldabbagh, K]]

[[Category: Peng, Y]]

[[Category: Yee, V C]]

[[Category: Designed insulin]]

[[Category: Hexamer]]

[[Category: Hormone]]

[[Category: Single chain]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5wdm is ON HOLD  until Paper Publication
+==An ultra-stable single-chain insulin analog resists thermal inactivation and exhibits biological signaling duration equivalent to the native protein==
+<StructureSection load='5wdm' size='340' side='right' caption='[[5wdm]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5wdm]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WDM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WDM FirstGlance]. <br>
-Description:
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wdm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wdm OCA], [http://pdbe.org/5wdm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wdm RCSB], [http://www.ebi.ac.uk/pdbsum/5wdm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wdm ProSAT]</span></td></tr>
-[[Category: Unreleased Structures]]
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/A6XGL2_HUMAN A6XGL2_HUMAN]] Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver (By similarity).[SAAS:SAAS022353_004_028339]
+__TOC__
+</StructureSection>
+[[Category: Aldabbagh, K]]
+[[Category: Peng, Y]]
+[[Category: Yee, V C]]
+[[Category: Designed insulin]]
+[[Category: Hexamer]]
+[[Category: Hormone]]
+[[Category: Single chain]]