5y53: Difference between revisions
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==Crystal structure of AL2 PAL domain in complex with AtBmi1a binding site== | |||
<StructureSection load='5y53' size='340' side='right' caption='[[5y53]], [[Resolution|resolution]] 1.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5y53]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Y53 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5Y53 FirstGlance]. <br> | |||
</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RING-type_E3_ubiquitin_transferase RING-type E3 ubiquitin transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.2.27 2.3.2.27] </span></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5y53 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5y53 OCA], [http://pdbe.org/5y53 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5y53 RCSB], [http://www.ebi.ac.uk/pdbsum/5y53 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5y53 ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/ALFL2_ARATH ALFL2_ARATH]] Histone-binding component that specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes. [[http://www.uniprot.org/uniprot/DRIP1_ARATH DRIP1_ARATH]] E3 ubiquitin-protein ligase that acts as a negative regulator of the response to water stress. Mediates ubiquitination and subsequent proteasomal degradation of the drought-induced transcriptional activator DREB2A. Functionally redundant with DRIP2.<ref>PMID:18552202</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: RING-type E3 ubiquitin transferase]] | |||
[[Category: Huang, Y]] | |||
[[Category: Peng, L]] | |||
[[Category: Wang, L L]] | |||
[[Category: Alfin-like family protein]] | |||
[[Category: Complex]] | |||
[[Category: Gene regulation]] | |||
[[Category: Prc1 interactor]] | |||