5y6f: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5y6f is ~~ON HOLD until Paper Publication~~

==Crystal structure of YcgR in complex with c-di-GMP from Escherichia coli==

~~Authors~~: ~~Hou~~, Y.J., ~~Wang~~, D.C., Li, D.F.

== Structural highlights ==

<table><tr><td colspan='2'>[[5y6f]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Y6F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5Y6F FirstGlance]. <br>

~~Description~~: ~~Crystal structure~~ of ~~YcgR~~ in ~~complex with~~ c-di-GMP ~~from Escherichia coli~~

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=C2E:9,9-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d 3,2-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one)'>C2E</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5y6f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5y6f OCA], [http://pdbe.org/5y6f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5y6f RCSB], [http://www.ebi.ac.uk/pdbsum/5y6f PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5y6f ProSAT]</span></td></tr>

[[Category: Wang, D.C]]

</table>

[[Category: ~~Hou, Y.J~~]]

== Function ==

[[Category: ~~Li, D.F~~]]

[[http://www.uniprot.org/uniprot/YCGR_ECOLI YCGR_ECOLI]] Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. When bound to c-di-GMP it binds to elements of the flagellar motor (MotA (PubMed:20303158) and/or FliG and FliM (PubMed:20346719), binding to FliM also occurs in the absence of c-di-GMP), causing the motor to slow down. Thus, increasing levels of c-di-GMP lead to decreased motility. Probably binds 1 c-di-GMP dimer per subunit.<ref>PMID:11031114</ref> <ref>PMID:16920715</ref> <ref>PMID:20303158</ref> <ref>PMID:20346719</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Hou, Y J]]

[[Category: Li, D F]]

[[Category: Wang, D C]]

[[Category: C-di-gmp binding]]

[[Category: Flagellar brake protein]]

[[Category: Motor protein binding]]

[[Category: Pilz domain]]

[[Category: Protein binding]]

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5y6f is ON HOLD  until Paper Publication
+==Crystal structure of YcgR in complex with c-di-GMP from Escherichia coli==
+<StructureSection load='5y6f' size='340' side='right' caption='[[5y6f]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
-Authors: Hou, Y.J., Wang, D.C., Li, D.F.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5y6f]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Y6F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5Y6F FirstGlance]. <br>
-Description: Crystal structure of YcgR in complex with c-di-GMP from Escherichia coli
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=C2E:9,9-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d 3,2-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one)'>C2E</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5y6f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5y6f OCA], [http://pdbe.org/5y6f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5y6f RCSB], [http://www.ebi.ac.uk/pdbsum/5y6f PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5y6f ProSAT]</span></td></tr>
-[[Category: Wang, D.C]]
+</table>
-[[Category: Hou, Y.J]]
+== Function ==
-[[Category: Li, D.F]]
+[[http://www.uniprot.org/uniprot/YCGR_ECOLI YCGR_ECOLI]] Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. When bound to c-di-GMP it binds to elements of the flagellar motor (MotA (PubMed:20303158) and/or FliG and FliM (PubMed:20346719), binding to FliM also occurs in the absence of c-di-GMP), causing the motor to slow down. Thus, increasing levels of c-di-GMP lead to decreased motility. Probably binds 1 c-di-GMP dimer per subunit.<ref>PMID:11031114</ref> <ref>PMID:16920715</ref> <ref>PMID:20303158</ref> <ref>PMID:20346719</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Hou, Y J]]
+[[Category: Li, D F]]
+[[Category: Wang, D C]]
+[[Category: C-di-gmp binding]]
+[[Category: Flagellar brake protein]]
+[[Category: Motor protein binding]]
+[[Category: Pilz domain]]
+[[Category: Protein binding]]