Retroviral Integrase: Difference between revisions
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[See below for a table of antiretroviral drugs with trade name, company, patents, and notes.] | [See below for a table of antiretroviral drugs with trade name, company, patents, and notes.] | ||
== | ==Mechanism for strand-transfer inhibition actio== | ||
[[Image:GAViralLifeCycle.jpg|thumb|alt=Alt text|Caption]] | [[Image:GAViralLifeCycle.jpg|thumb|alt=Alt text|Caption]] | ||
[[Image:Strand Inhibition.jpg|thumb|alt=Alt text|Above is a JMOL image of MK-0518 blocking the 3' end of the viral DNA from binding the active site. Notice the metal chelating oxygen atoms in MK-0518 interacting with the magnesium cations found in the active site.]] | [[Image:Strand Inhibition.jpg|thumb|alt=Alt text|Above is a JMOL image of MK-0518 blocking the 3' end of the viral DNA from binding the active site. Notice the metal chelating oxygen atoms in MK-0518 interacting with the magnesium cations found in the active site.]] | ||
