5yew: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5yew is ~~ON HOLD~~

==Structural basis for GTP hydrolysis and conformational change of mitofusin 1 in mediating mitochondrial fusion==

~~Authors~~: ~~Liming~~, Y., ~~Yuanbo~~, Q., ~~Xiaofang~~, H.~~, Caiting, Y~~.

== Structural highlights ==

<table><tr><td colspan='2'>[[5yew]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YEW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5YEW FirstGlance]. <br>

~~Description~~: ~~Structural basis for GTP hydrolysis~~ and ~~conformational change~~ of ~~mitofusin 1 in mediating~~ mitochondrial ~~fusion~~

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BEF:BERYLLIUM+TRIFLUORIDE+ION'>BEF</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5yew FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5yew OCA], [http://pdbe.org/5yew PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5yew RCSB], [http://www.ebi.ac.uk/pdbsum/5yew PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5yew ProSAT]</span></td></tr>

[[Category: ~~Xiaofang~~, H]]

</table>

[[Category: ~~Liming~~, Y]]

== Function ==

[[Category: ~~Yuanbo~~, Q]]

[[http://www.uniprot.org/uniprot/MFN1_HUMAN MFN1_HUMAN]] Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN1 acts independently of the cytoskeleton. Overexpression induces the formation of mitochondrial networks.<ref>PMID:11181170</ref> <ref>PMID:12475957</ref> <ref>PMID:12759376</ref> <ref>PMID:23921378</ref>

[[Category: ~~Caiting, Y~~]]

== References ==

__TOC__

</StructureSection>

[[Category: Huang, X]]

[[Category: Qi, Y]]

[[Category: Yan, L]]

[[Category: Yu, C]]

[[Category: Fusion]]

[[Category: Hydrolase]]

[[Category: Mfn1]]

[[Category: Mitochondria]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5yew is ON HOLD
+==Structural basis for GTP hydrolysis and conformational change of mitofusin 1 in mediating mitochondrial fusion==
+<StructureSection load='5yew' size='340' side='right' caption='[[5yew]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
-Authors: Liming, Y., Yuanbo, Q., Xiaofang, H., Caiting, Y.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5yew]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YEW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5YEW FirstGlance]. <br>
-Description: Structural basis for GTP hydrolysis and conformational change of mitofusin 1 in mediating mitochondrial fusion
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BEF:BERYLLIUM+TRIFLUORIDE+ION'>BEF</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5yew FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5yew OCA], [http://pdbe.org/5yew PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5yew RCSB], [http://www.ebi.ac.uk/pdbsum/5yew PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5yew ProSAT]</span></td></tr>
-[[Category: Xiaofang, H]]
+</table>
-[[Category: Liming, Y]]
+== Function ==
-[[Category: Yuanbo, Q]]
+[[http://www.uniprot.org/uniprot/MFN1_HUMAN MFN1_HUMAN]] Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN1 acts independently of the cytoskeleton. Overexpression induces the formation of mitochondrial networks.<ref>PMID:11181170</ref> <ref>PMID:12475957</ref> <ref>PMID:12759376</ref> <ref>PMID:23921378</ref>
-[[Category: Caiting, Y]]
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Huang, X]]
+[[Category: Qi, Y]]
+[[Category: Yan, L]]
+[[Category: Yu, C]]
+[[Category: Fusion]]
+[[Category: Hydrolase]]
+[[Category: Mfn1]]
+[[Category: Mitochondria]]