6aqf: Difference between revisions

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'''Unreleased structure'''


The entry 6aqf is ON HOLD  until Paper Publication
==Crystal structure of A2AAR-BRIL in complex with the antagonist ZM241385 produced from Pichia pastoris==
 
<StructureSection load='6aqf' size='340' side='right' caption='[[6aqf]], [[Resolution|resolution]] 2.51&Aring;' scene=''>
Authors: Eddy, M.T., Lee, M.Y., Gao, Z., White, K., Didenko, T., Horst, R., Audet, M., Stanczak, P., McClary, K.M., Han, G.W., Jacobson, K.A., Stevens, R.C., Wuthrich, K.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[6aqf]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AQF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6AQF FirstGlance]. <br>
Description: Crystal structure of A2AAR-BRIL in complex with the antagonist ZM241385 produced from Pichia pastoris
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=OLB:(2S)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLB</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene>, <scene name='pdbligand=ZMA:4-{2-[(7-AMINO-2-FURAN-2-YL[1,2,4]TRIAZOLO[1,5-A][1,3,5]TRIAZIN-5-YL)AMINO]ETHYL}PHENOL'>ZMA</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6aqf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6aqf OCA], [http://pdbe.org/6aqf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6aqf RCSB], [http://www.ebi.ac.uk/pdbsum/6aqf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6aqf ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/AA2AR_HUMAN AA2AR_HUMAN]] Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.  
__TOC__
</StructureSection>
[[Category: Audet, M]]
[[Category: Didenko, T]]
[[Category: Eddy, M T]]
[[Category: Gao, Z]]
[[Category: Han, G W]]
[[Category: Horst, R]]
[[Category: Horst, R]]
[[Category: Jacobson, K A]]
[[Category: Lee, M Y]]
[[Category: McClary, K M]]
[[Category: Stanczak, P]]
[[Category: Stevens, R C]]
[[Category: White, K]]
[[Category: Wuthrich, K]]
[[Category: Wuthrich, K]]
[[Category: Stevens, R.C]]
[[Category: A2aar]]
[[Category: Gao, Z]]
[[Category: Adenosine receptor]]
[[Category: White, K]]
[[Category: Antagonist complex]]
[[Category: Han, G.W]]
[[Category: Gpcr]]
[[Category: Audet, M]]
[[Category: Human a2aar_bril chimera]]
[[Category: Stanczak, P]]
[[Category: Lcp]]
[[Category: Eddy, M.T]]
[[Category: Membrane protein]]
[[Category: Lee, M.Y]]
[[Category: Pichia pastori]]
[[Category: Jacobson, K.A]]
[[Category: Didenko, T]]
[[Category: Mcclary, K.M]]
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