6ay9: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6ay9 is ~~ON HOLD~~ ~~until Sep 07 2019~~

==Structure of the native full-length HIV-1 capsid protein in complex with CPSF6 peptide==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[6ay9]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AY9 OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6AY9 FirstGlance].

~~Description~~:

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[4xfx|4xfx]]</td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ay9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ay9 OCA], [http://pdbe.org/6ay9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ay9 RCSB], [http://www.ebi.ac.uk/pdbsum/6ay9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ay9 ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/CPSF6_HUMAN CPSF6_HUMAN]] Component of the cleavage factor Im complex (CFIm) that plays a key role in pre-mRNA 3'-processing. Involved in association with NUDT21/CPSF5 in pre-MRNA 3'-end poly(A) site cleavage and poly(A) addition. CPSF6 binds to cleavage and polyadenylation RNA substrates and promotes RNA looping.<ref>PMID:9659921</ref> <ref>PMID:8626397</ref> <ref>PMID:14690600</ref> <ref>PMID:20695905</ref> <ref>PMID:21295486</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Gres, A T]]

[[Category: Kirby, K A]]

[[Category: Sarafianos, S G]]

[[Category: Cpsf6 complex]]

[[Category: Hexamer]]

[[Category: Hiv-1 capsid protein]]

[[Category: Viral protein]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6ay9 is ON HOLD  until Sep 07 2019
+==Structure of the native full-length HIV-1 capsid protein in complex with CPSF6 peptide==
+<StructureSection load='6ay9' size='340' side='right' caption='[[6ay9]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6ay9]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AY9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6AY9 FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4xfx|4xfx]]</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ay9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ay9 OCA], [http://pdbe.org/6ay9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ay9 RCSB], [http://www.ebi.ac.uk/pdbsum/6ay9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ay9 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/CPSF6_HUMAN CPSF6_HUMAN]] Component of the cleavage factor Im complex (CFIm) that plays a key role in pre-mRNA 3'-processing. Involved in association with NUDT21/CPSF5 in pre-MRNA 3'-end poly(A) site cleavage and poly(A) addition. CPSF6 binds to cleavage and polyadenylation RNA substrates and promotes RNA looping.<ref>PMID:9659921</ref> <ref>PMID:8626397</ref> <ref>PMID:14690600</ref> <ref>PMID:20695905</ref> <ref>PMID:21295486</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Gres, A T]]
+[[Category: Kirby, K A]]
+[[Category: Sarafianos, S G]]
+[[Category: Cpsf6 complex]]
+[[Category: Hexamer]]
+[[Category: Hiv-1 capsid protein]]
+[[Category: Viral protein]]