6ayo: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6ayo is ~~ON HOLD until Paper Publication~~

==Crystal structure of Campylobacter jejuni 5'-methylthioadenosine/S-adenosyl homocysteine nucleosidase (MTAN) complexed with 5'-deoxy-5'-Propyl-DADMe-Immucillin-A==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[6ayo]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AYO OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6AYO FirstGlance].

~~Description~~:

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene>, <scene name='pdbligand=C1Y:(3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-propylpyrrolidin-3-ol'>C1Y</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Adenosylhomocysteine_nucleosidase Adenosylhomocysteine nucleosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.9 3.2.2.9] </td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ayo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ayo OCA], [http://pdbe.org/6ayo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ayo RCSB], [http://www.ebi.ac.uk/pdbsum/6ayo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ayo ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/A0A1E7P7U4_CAMJU A0A1E7P7U4_CAMJU]] Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.[SAAS:SAAS00679308]

__TOC__

</StructureSection>

[[Category: Adenosylhomocysteine nucleosidase]]

[[Category: Almo, S C]]

[[Category: Bonanno, J B]]

[[Category: Ducati, R G]]

[[Category: Harijan, R K]]

[[Category: Schramm, V L]]

[[Category: Foodborne disease]]

[[Category: Hydrolase]]

[[Category: Mtan enzyme]]

[[Category: Transferase]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6ayo is ON HOLD  until Paper Publication
+==Crystal structure of Campylobacter jejuni 5'-methylthioadenosine/S-adenosyl homocysteine nucleosidase (MTAN) complexed with 5'-deoxy-5'-Propyl-DADMe-Immucillin-A==
+<StructureSection load='6ayo' size='340' side='right' caption='[[6ayo]], [[Resolution|resolution]] 1.67&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6ayo]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AYO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6AYO FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene>, <scene name='pdbligand=C1Y:(3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-propylpyrrolidin-3-ol'>C1Y</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenosylhomocysteine_nucleosidase Adenosylhomocysteine nucleosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.9 3.2.2.9] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ayo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ayo OCA], [http://pdbe.org/6ayo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ayo RCSB], [http://www.ebi.ac.uk/pdbsum/6ayo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ayo ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/A0A1E7P7U4_CAMJU A0A1E7P7U4_CAMJU]] Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.[SAAS:SAAS00679308]
+__TOC__
+</StructureSection>
+[[Category: Adenosylhomocysteine nucleosidase]]
+[[Category: Almo, S C]]
+[[Category: Bonanno, J B]]
+[[Category: Ducati, R G]]
+[[Category: Harijan, R K]]
+[[Category: Schramm, V L]]
+[[Category: Foodborne disease]]
+[[Category: Hydrolase]]
+[[Category: Mtan enzyme]]
+[[Category: Transferase]]