2fwq: Difference between revisions

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==Reduced enolate chromophore intermediate for Y66H GFP variant==
==Reduced enolate chromophore intermediate for Y66H GFP variant==
<StructureSection load='2fwq' size='340' side='right' caption='[[2fwq]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
<StructureSection load='2fwq' size='340' side='right'caption='[[2fwq]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2fwq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Aeqvi Aeqvi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FWQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FWQ FirstGlance]. <br>
<table><tr><td colspan='2'>[[2fwq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aeqvi Aeqvi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FWQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FWQ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=XXY:2-[(1R,2R)-1-AMINO-2-HYDROXYPROPYL]-1-(CARBOXYMETHYL)-4-(1H-IMIDAZOL-5-YLMETHYL)-1H-IMIDAZOL-5-OLATE'>XXY</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=XXY:2-[(1R,2R)-1-AMINO-2-HYDROXYPROPYL]-1-(CARBOXYMETHYL)-4-(1H-IMIDAZOL-5-YLMETHYL)-1H-IMIDAZOL-5-OLATE'>XXY</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GFP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6100 AEQVI])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GFP ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6100 AEQVI])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fwq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fwq OCA], [http://pdbe.org/2fwq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2fwq RCSB], [http://www.ebi.ac.uk/pdbsum/2fwq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2fwq ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fwq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fwq OCA], [https://pdbe.org/2fwq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fwq RCSB], [https://www.ebi.ac.uk/pdbsum/2fwq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fwq ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/GFP_AEQVI GFP_AEQVI]] Energy-transfer acceptor. Its role is to transduce the blue chemiluminescence of the protein aequorin into green fluorescent light by energy transfer. Fluoresces in vivo upon receiving energy from the Ca(2+)-activated photoprotein aequorin.  
[[https://www.uniprot.org/uniprot/GFP_AEQVI GFP_AEQVI]] Energy-transfer acceptor. Its role is to transduce the blue chemiluminescence of the protein aequorin into green fluorescent light by energy transfer. Fluoresces in vivo upon receiving energy from the Ca(2+)-activated photoprotein aequorin.  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fw/2fwq_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fw/2fwq_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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</div>
</div>
<div class="pdbe-citations 2fwq" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 2fwq" style="background-color:#fffaf0;"></div>
==See Also==
*[[Green Fluorescent Protein 3D structures|Green Fluorescent Protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Aeqvi]]
[[Category: Aeqvi]]
[[Category: Large Structures]]
[[Category: Barondeau, D P]]
[[Category: Barondeau, D P]]
[[Category: Getzoff, E D]]
[[Category: Getzoff, E D]]